Diffuse alveolar hemorrhage as a manifestation of Behçet disease

Research output: Contribution to journalArticle

Abstract

Diffuse alveolar hemorrhage (DAH) is a rare life-threatening condition which refers to the presence of red blood cells within alveoli deriving from hemorrhage originating in the pulmonary microvasculature. It differs from alveolar filling, in which blood cells derive from localized bleeding, usually of bronchial origin. DAH may be part of diffuse alveolar injury of any origin. DAH should be considered a medical emergency due to the significant morbidity and mortality associated with respiratory failure, when secondary to impaired oxygen uptake from alveoli filled with erythrocytes. Patients with alveolar hemorrhage present with non-specific symptoms like dyspnea, cough and hemoptysis, which is not always present. They may develop acutely or insidiously over a few days. We present a case of a patient with probable Behçet's disease complicated by pulmonary capillaritis and DAH resulting in refractory respiratory failure and death.

Original languageEnglish
Pages (from-to)138-141
Number of pages4
JournalReumatismo
Volume65
Issue number3
DOIs
Publication statusPublished - 2013

Fingerprint

Hemorrhage
Respiratory Insufficiency
Erythrocytes
Hemoptysis
Microvessels
Cough
Dyspnea
Lung Diseases
Blood Cells
Emergencies
Oxygen
Morbidity
Lung
Mortality
Wounds and Injuries

Keywords

  • Alveolar hemorrhage
  • Behçet disease
  • Vasculitis

ASJC Scopus subject areas

  • Rheumatology

Cite this

Diffuse alveolar hemorrhage as a manifestation of Behçet disease. / Grosso, V.; Boveri, E.; Bogliolo, L.; Montecucco, C.; Caporali, R.

In: Reumatismo, Vol. 65, No. 3, 2013, p. 138-141.

Research output: Contribution to journalArticle

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