Diffuse malignant peritoneal mesothelioma: Systematic review of clinical management and biological research

Dario Baratti, Shigeki Kusamura, Marcello Deraco

Research output: Contribution to journalArticle

Abstract

Diffuse malignant peritoneal mesothelioma (DMPM) is an uncommon and locally aggressive tumor with poor prognosis. Currently, no standard therapy is available. The biology of this disease is still poorly understood. We performed a systematic search of relevant studies on clinical management and biological research of DMPM. Trials were selected using a predetermined protocol. The current evidence suggests that cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (PIC) results in improved survival. Biological understanding of DMPM is currently evolving.

Original languageEnglish
Pages (from-to)822-831
Number of pages10
JournalJournal of Surgical Oncology
Volume103
Issue number8
DOIs
Publication statusPublished - Jun 2011

Keywords

  • EGFR
  • hyperthermic intraperitoneal chemotherapy (HIPEC)
  • peritonectomy
  • receptor tyrosine-kinase
  • telomerase

ASJC Scopus subject areas

  • Surgery
  • Oncology

Fingerprint Dive into the research topics of 'Diffuse malignant peritoneal mesothelioma: Systematic review of clinical management and biological research'. Together they form a unique fingerprint.

  • Cite this