Diffusely infiltrating gliomas

F. R. Buttarelli, M. Antonelli, F. Giangaspero

Research output: Contribution to journalArticlepeer-review


Diffusely infiltranting gliomas are the most frequent intracranial tumours, accouting for 60% of brain neoplasm of the adults. According to World Health Organization classification, diffuse gliomas include astrocytomas (diffuse astrocytomas grade II, anaplastic astrocytomas grade III and glioblastomas grade IV), oligodendrogliomas (oligodendrogliomas grade II, anaplastic oligodendrogliomas grade III) and mixed gliomas (oligoastrocytoma grade II and anaplastic oligoastrocytomas grade III). We describe neuropathological aspects of these neoplasm and several alterations playing a crucial role in their malignant transformation.

Original languageEnglish
Pages (from-to)31-38
Number of pages8
JournalRivista Medica
Issue number4
Publication statusPublished - Dec 2007


  • Diffuse gliomas
  • Grading of gliomas
  • Histopathology
  • Molecular biology

ASJC Scopus subject areas

  • Medicine(all)


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