Diffusion tensor imaging and tractography to evaluate sacral nerve root abnormalities in endometriosis-related pain

A pilot study

L. Manganaro, M. G. Porpora, V. Vinci, S. Bernardo, P. Lodise, P. Sollazzo, M. E. Sergi, M. Saldari, G. Pace, G. Vittori, C. Catalano, P. Pantano

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objective: To prospectively evaluate microstructural abnormalities in sacral nerve roots in women affected by chronic pelvic pain associated with endometriosis. Methods: We enrolled 30 women with an ultrasound diagnosis of endometriosis and moderate-severe chronic pelvic pain; 10 age-matched healthy women comprised the control group. All subjects underwent 3 T magnetic resonance imaging (MRI), including diffusion tensor imaging (DTI); the sacral roots were reconstructed by post-processing the DTI data with dedicated software. Mean fractional anisotropy (FA) values in the S1, S2 and S3 roots were quantified. Analysis of FA values was performed by two radiologists in order to evaluate the interobserver agreement. Results: The sacral nerve roots in healthy subjects were clearly visualised. Most of the patients with endometriosis displayed abnormalities of S1, S2 and S3 bilaterally at tractography, including an irregular and disorganised appearance. FAvalues in the S1, S2 and S3 roots were significantly lower in patients than in controls (P

Original languageEnglish
Pages (from-to)95-101
Number of pages7
JournalEuropean Radiology
Volume24
Issue number1
DOIs
Publication statusPublished - Jan 2014

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Diffusion Tensor Imaging
Endometriosis
Pelvic Pain
Anisotropy
Pain
Chronic Pain
Healthy Volunteers
Software
Magnetic Resonance Imaging
Control Groups

Keywords

  • Chronic pelvic pain
  • DTI
  • Endometriosis
  • PelvicMRI
  • Tractography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Diffusion tensor imaging and tractography to evaluate sacral nerve root abnormalities in endometriosis-related pain : A pilot study. / Manganaro, L.; Porpora, M. G.; Vinci, V.; Bernardo, S.; Lodise, P.; Sollazzo, P.; Sergi, M. E.; Saldari, M.; Pace, G.; Vittori, G.; Catalano, C.; Pantano, P.

In: European Radiology, Vol. 24, No. 1, 01.2014, p. 95-101.

Research output: Contribution to journalArticle

Manganaro, L, Porpora, MG, Vinci, V, Bernardo, S, Lodise, P, Sollazzo, P, Sergi, ME, Saldari, M, Pace, G, Vittori, G, Catalano, C & Pantano, P 2014, 'Diffusion tensor imaging and tractography to evaluate sacral nerve root abnormalities in endometriosis-related pain: A pilot study', European Radiology, vol. 24, no. 1, pp. 95-101. https://doi.org/10.1007/s00330-013-2981-0
Manganaro, L. ; Porpora, M. G. ; Vinci, V. ; Bernardo, S. ; Lodise, P. ; Sollazzo, P. ; Sergi, M. E. ; Saldari, M. ; Pace, G. ; Vittori, G. ; Catalano, C. ; Pantano, P. / Diffusion tensor imaging and tractography to evaluate sacral nerve root abnormalities in endometriosis-related pain : A pilot study. In: European Radiology. 2014 ; Vol. 24, No. 1. pp. 95-101.
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