TY - JOUR
T1 - Diffusion weighted imaging and apparent diffusion coefficient in 3 tesla magnetic resonance imaging of breast lesions
AU - Caivano, Rocchina
AU - Villonio, Antonio
AU - D'Antuono, Felice
AU - Gioioso, Matilde
AU - Rabasco, Paola
AU - Iannelli, Giancarlo
AU - Zandolino, Alexis
AU - Lotumolo, Antonella
AU - Dinardo, Giuseppina
AU - Macarini, Luca
AU - Guglielmi, Giuseppe
AU - Cammarota, Aldo
PY - 2015/5/28
Y1 - 2015/5/28
N2 - Objective: To evaluate the utility of diffusion-weighted-imaging (DWI) and apparent-diffusion-coefficient (ADC) in a 3T magnetic-resonance-imaging (MRI) study of breast cancer. In particular, the study aims to classify ADC-values according to histology either for benign or malignant lesions. Methods: 110 Breast MRI with MRI-DWI sequences and quantitative evaluation of the ADC were retrospectively reviewed. Results obtained with MRI-DWI and with biopsy were analyzed and ADC values were compared to histological results. Results: MRI showed a 95.5% sensitivity and a 83.7% specificity. The mean ADC values of benign and malignant lesions were 2.06 ± 0.19 and 1.03 ± 0.07 mm/s, respectively (p <.05). Conclusions: DWI and ADC-values could help distinguishing malignant and benign breast masses.
AB - Objective: To evaluate the utility of diffusion-weighted-imaging (DWI) and apparent-diffusion-coefficient (ADC) in a 3T magnetic-resonance-imaging (MRI) study of breast cancer. In particular, the study aims to classify ADC-values according to histology either for benign or malignant lesions. Methods: 110 Breast MRI with MRI-DWI sequences and quantitative evaluation of the ADC were retrospectively reviewed. Results obtained with MRI-DWI and with biopsy were analyzed and ADC values were compared to histological results. Results: MRI showed a 95.5% sensitivity and a 83.7% specificity. The mean ADC values of benign and malignant lesions were 2.06 ± 0.19 and 1.03 ± 0.07 mm/s, respectively (p <.05). Conclusions: DWI and ADC-values could help distinguishing malignant and benign breast masses.
KW - 3T magnetic resonance imaging
KW - Apparent diffusion coefficient
KW - Breast cancer
KW - Diffusion weighted imaging
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U2 - 10.3109/07357907.2015.1019674
DO - 10.3109/07357907.2015.1019674
M3 - Article
C2 - 25831024
AN - SCOPUS:84929845024
VL - 33
SP - 159
EP - 164
JO - Cancer Investigation
JF - Cancer Investigation
SN - 0735-7907
IS - 5
ER -