Diffusion weighted imaging and apparent diffusion coefficient in 3 tesla magnetic resonance imaging of breast lesions

Rocchina Caivano; Antonio Villonio; Felice D'Antuono; Matilde Gioioso; Paola Rabasco; Giancarlo Iannelli; Alexis Zandolino; Antonella Lotumolo; Giuseppina Dinardo; Luca Macarini; Giuseppe Guglielmi; Aldo Cammarota

doi:10.3109/07357907.2015.1019674

Diffusion weighted imaging and apparent diffusion coefficient in 3 tesla magnetic resonance imaging of breast lesions

Rocchina Caivano, Antonio Villonio, Felice D'Antuono, Matilde Gioioso, Paola Rabasco, Giancarlo Iannelli, Alexis Zandolino, Antonella Lotumolo, Giuseppina Dinardo, Luca Macarini, Giuseppe Guglielmi, Aldo Cammarota

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: To evaluate the utility of diffusion-weighted-imaging (DWI) and apparent-diffusion-coefficient (ADC) in a 3T magnetic-resonance-imaging (MRI) study of breast cancer. In particular, the study aims to classify ADC-values according to histology either for benign or malignant lesions. Methods: 110 Breast MRI with MRI-DWI sequences and quantitative evaluation of the ADC were retrospectively reviewed. Results obtained with MRI-DWI and with biopsy were analyzed and ADC values were compared to histological results. Results: MRI showed a 95.5% sensitivity and a 83.7% specificity. The mean ADC values of benign and malignant lesions were 2.06 ± 0.19 and 1.03 ± 0.07 mm/s, respectively (p <.05). Conclusions: DWI and ADC-values could help distinguishing malignant and benign breast masses.

Original language	English
Pages (from-to)	159-164
Number of pages	6
Journal	Cancer Investigation
Volume	33
Issue number	5
DOIs	https://doi.org/10.3109/07357907.2015.1019674
Publication status	Published - May 28 2015

Keywords

3T magnetic resonance imaging
Apparent diffusion coefficient
Breast cancer
Diffusion weighted imaging

ASJC Scopus subject areas

Cancer Research
Oncology
Medicine(all)

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Caivano, R., Villonio, A., D'Antuono, F., Gioioso, M., Rabasco, P., Iannelli, G., Zandolino, A., Lotumolo, A., Dinardo, G., Macarini, L., Guglielmi, G., & Cammarota, A. (2015). Diffusion weighted imaging and apparent diffusion coefficient in 3 tesla magnetic resonance imaging of breast lesions. Cancer Investigation, 33(5), 159-164. https://doi.org/10.3109/07357907.2015.1019674

Caivano, R, Villonio, A, D'Antuono, F, Gioioso, M, Rabasco, P, Iannelli, G, Zandolino, A, Lotumolo, A, Dinardo, G, Macarini, L, Guglielmi, G & Cammarota, A 2015, 'Diffusion weighted imaging and apparent diffusion coefficient in 3 tesla magnetic resonance imaging of breast lesions', Cancer Investigation, vol. 33, no. 5, pp. 159-164. https://doi.org/10.3109/07357907.2015.1019674

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abstract = "Objective: To evaluate the utility of diffusion-weighted-imaging (DWI) and apparent-diffusion-coefficient (ADC) in a 3T magnetic-resonance-imaging (MRI) study of breast cancer. In particular, the study aims to classify ADC-values according to histology either for benign or malignant lesions. Methods: 110 Breast MRI with MRI-DWI sequences and quantitative evaluation of the ADC were retrospectively reviewed. Results obtained with MRI-DWI and with biopsy were analyzed and ADC values were compared to histological results. Results: MRI showed a 95.5% sensitivity and a 83.7% specificity. The mean ADC values of benign and malignant lesions were 2.06 ± 0.19 and 1.03 ± 0.07 mm/s, respectively (p <.05). Conclusions: DWI and ADC-values could help distinguishing malignant and benign breast masses.",

keywords = "3T magnetic resonance imaging, Apparent diffusion coefficient, Breast cancer, Diffusion weighted imaging",

author = "Rocchina Caivano and Antonio Villonio and Felice D'Antuono and Matilde Gioioso and Paola Rabasco and Giancarlo Iannelli and Alexis Zandolino and Antonella Lotumolo and Giuseppina Dinardo and Luca Macarini and Giuseppe Guglielmi and Aldo Cammarota",

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doi = "10.3109/07357907.2015.1019674",

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AU - Caivano, Rocchina

AU - Villonio, Antonio

AU - D'Antuono, Felice

AU - Gioioso, Matilde

AU - Rabasco, Paola

AU - Iannelli, Giancarlo

AU - Zandolino, Alexis

AU - Lotumolo, Antonella

AU - Dinardo, Giuseppina

AU - Macarini, Luca

AU - Guglielmi, Giuseppe

AU - Cammarota, Aldo

PY - 2015/5/28

Y1 - 2015/5/28

N2 - Objective: To evaluate the utility of diffusion-weighted-imaging (DWI) and apparent-diffusion-coefficient (ADC) in a 3T magnetic-resonance-imaging (MRI) study of breast cancer. In particular, the study aims to classify ADC-values according to histology either for benign or malignant lesions. Methods: 110 Breast MRI with MRI-DWI sequences and quantitative evaluation of the ADC were retrospectively reviewed. Results obtained with MRI-DWI and with biopsy were analyzed and ADC values were compared to histological results. Results: MRI showed a 95.5% sensitivity and a 83.7% specificity. The mean ADC values of benign and malignant lesions were 2.06 ± 0.19 and 1.03 ± 0.07 mm/s, respectively (p <.05). Conclusions: DWI and ADC-values could help distinguishing malignant and benign breast masses.

AB - Objective: To evaluate the utility of diffusion-weighted-imaging (DWI) and apparent-diffusion-coefficient (ADC) in a 3T magnetic-resonance-imaging (MRI) study of breast cancer. In particular, the study aims to classify ADC-values according to histology either for benign or malignant lesions. Methods: 110 Breast MRI with MRI-DWI sequences and quantitative evaluation of the ADC were retrospectively reviewed. Results obtained with MRI-DWI and with biopsy were analyzed and ADC values were compared to histological results. Results: MRI showed a 95.5% sensitivity and a 83.7% specificity. The mean ADC values of benign and malignant lesions were 2.06 ± 0.19 and 1.03 ± 0.07 mm/s, respectively (p <.05). Conclusions: DWI and ADC-values could help distinguishing malignant and benign breast masses.

KW - 3T magnetic resonance imaging

KW - Apparent diffusion coefficient

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KW - Diffusion weighted imaging

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Diffusion weighted imaging and apparent diffusion coefficient in 3 tesla magnetic resonance imaging of breast lesions

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