Diffusion-weighted magnetic resonance imaging in patients with prostate cancer treated with radiotherapy

Giancarlo Iannelli; Rocchina Caivano; Luciana Rago; Vittorio Simeon; Antonella Lotumolo; Paola Rabasco; Antonio Villonio; Matilde Gioioso; Pietro Mastrangelo; Flavio Barchetti; Valeria Panebianco; Luca Macarini; Giuseppe Guglielmi; Aldo Cammarota

doi:10.5301/tj.5000415

Diffusion-weighted magnetic resonance imaging in patients with prostate cancer treated with radiotherapy

Giancarlo Iannelli, Rocchina Caivano, Luciana Rago, Vittorio Simeon, Antonella Lotumolo, Paola Rabasco, Antonio Villonio, Matilde Gioioso, Pietro Mastrangelo, Flavio Barchetti, Valeria Panebianco, Luca Macarini, Giuseppe Guglielmi, Aldo Cammarota

Research output: Contribution to journal › Article › peer-review

Abstract

Aims: To evaluate the utility of a multiparametric 3T magnetic resonance imaging (MRI) study using diffusion-weighted images (DWI) for the assessment of prostate cancer before and after radiotherapy (RT). Methods: A total of 34 patients, who received a histologic diagnosis of prostate adenocarcinoma, underwent MRI examination before and after local RT for the assessment of response to treatment. Apparent diffusion coefficient (ADC) values were calculated and compared. Results: Before RT, DWI shows pathologic restriction of signal, while after RT pathologic restriction of signal was reduced or disappeared. The ADC values were significantly increased after therapy (p

Original language	English
Pages (from-to)	71-76
Number of pages	6
Journal	Tumori
Volume	102
Issue number	1
DOIs	https://doi.org/10.5301/tj.5000415
Publication status	Published - Jan 1 2016

Keywords

Apparent diffusion coefficient
Diffusion-weighed imaging
Magnetic resonance imaging
Prostate cancer
Response to therapy

ASJC Scopus subject areas

Cancer Research
Oncology

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10.5301/tj.5000415

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abstract = "Aims: To evaluate the utility of a multiparametric 3T magnetic resonance imaging (MRI) study using diffusion-weighted images (DWI) for the assessment of prostate cancer before and after radiotherapy (RT). Methods: A total of 34 patients, who received a histologic diagnosis of prostate adenocarcinoma, underwent MRI examination before and after local RT for the assessment of response to treatment. Apparent diffusion coefficient (ADC) values were calculated and compared. Results: Before RT, DWI shows pathologic restriction of signal, while after RT pathologic restriction of signal was reduced or disappeared. The ADC values were significantly increased after therapy (p",

keywords = "Apparent diffusion coefficient, Diffusion-weighed imaging, Magnetic resonance imaging, Prostate cancer, Response to therapy",

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AU - Iannelli, Giancarlo

AU - Caivano, Rocchina

AU - Rago, Luciana

AU - Simeon, Vittorio

AU - Lotumolo, Antonella

AU - Rabasco, Paola

AU - Villonio, Antonio

AU - Gioioso, Matilde

AU - Mastrangelo, Pietro

AU - Barchetti, Flavio

AU - Panebianco, Valeria

AU - Macarini, Luca

AU - Guglielmi, Giuseppe

AU - Cammarota, Aldo

PY - 2016/1/1

Y1 - 2016/1/1

N2 - Aims: To evaluate the utility of a multiparametric 3T magnetic resonance imaging (MRI) study using diffusion-weighted images (DWI) for the assessment of prostate cancer before and after radiotherapy (RT). Methods: A total of 34 patients, who received a histologic diagnosis of prostate adenocarcinoma, underwent MRI examination before and after local RT for the assessment of response to treatment. Apparent diffusion coefficient (ADC) values were calculated and compared. Results: Before RT, DWI shows pathologic restriction of signal, while after RT pathologic restriction of signal was reduced or disappeared. The ADC values were significantly increased after therapy (p

AB - Aims: To evaluate the utility of a multiparametric 3T magnetic resonance imaging (MRI) study using diffusion-weighted images (DWI) for the assessment of prostate cancer before and after radiotherapy (RT). Methods: A total of 34 patients, who received a histologic diagnosis of prostate adenocarcinoma, underwent MRI examination before and after local RT for the assessment of response to treatment. Apparent diffusion coefficient (ADC) values were calculated and compared. Results: Before RT, DWI shows pathologic restriction of signal, while after RT pathologic restriction of signal was reduced or disappeared. The ADC values were significantly increased after therapy (p

KW - Apparent diffusion coefficient

KW - Diffusion-weighed imaging

KW - Magnetic resonance imaging

KW - Prostate cancer

KW - Response to therapy

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Diffusion-weighted magnetic resonance imaging in patients with prostate cancer treated with radiotherapy

Abstract

Keywords

ASJC Scopus subject areas

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