Diffusion-weighted magnetic resonance imaging in patients with prostate cancer treated with radiotherapy

Giancarlo Iannelli, Rocchina Caivano, Luciana Rago, Vittorio Simeon, Antonella Lotumolo, Paola Rabasco, Antonio Villonio, Matilde Gioioso, Pietro Mastrangelo, Flavio Barchetti, Valeria Panebianco, Luca Macarini, Giuseppe Guglielmi, Aldo Cammarota

Research output: Contribution to journalArticlepeer-review


Aims: To evaluate the utility of a multiparametric 3T magnetic resonance imaging (MRI) study using diffusion-weighted images (DWI) for the assessment of prostate cancer before and after radiotherapy (RT). Methods: A total of 34 patients, who received a histologic diagnosis of prostate adenocarcinoma, underwent MRI examination before and after local RT for the assessment of response to treatment. Apparent diffusion coefficient (ADC) values were calculated and compared. Results: Before RT, DWI shows pathologic restriction of signal, while after RT pathologic restriction of signal was reduced or disappeared. The ADC values were significantly increased after therapy (p

Original languageEnglish
Pages (from-to)71-76
Number of pages6
Issue number1
Publication statusPublished - Jan 1 2016


  • Apparent diffusion coefficient
  • Diffusion-weighed imaging
  • Magnetic resonance imaging
  • Prostate cancer
  • Response to therapy

ASJC Scopus subject areas

  • Cancer Research
  • Oncology


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