Abstract
Aims: To evaluate the utility of a multiparametric 3T magnetic resonance imaging (MRI) study using diffusion-weighted images (DWI) for the assessment of prostate cancer before and after radiotherapy (RT). Methods: A total of 34 patients, who received a histologic diagnosis of prostate adenocarcinoma, underwent MRI examination before and after local RT for the assessment of response to treatment. Apparent diffusion coefficient (ADC) values were calculated and compared. Results: Before RT, DWI shows pathologic restriction of signal, while after RT pathologic restriction of signal was reduced or disappeared. The ADC values were significantly increased after therapy (p
| Original language | English |
|---|---|
| Pages (from-to) | 71-76 |
| Number of pages | 6 |
| Journal | Tumori |
| Volume | 102 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1 2016 |
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Keywords
- Apparent diffusion coefficient
- Diffusion-weighed imaging
- Magnetic resonance imaging
- Prostate cancer
- Response to therapy
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Diffusion-weighted magnetic resonance imaging in patients with prostate cancer treated with radiotherapy. / Iannelli, Giancarlo; Caivano, Rocchina; Rago, Luciana; Simeon, Vittorio; Lotumolo, Antonella; Rabasco, Paola; Villonio, Antonio; Gioioso, Matilde; Mastrangelo, Pietro; Barchetti, Flavio; Panebianco, Valeria; Macarini, Luca; Guglielmi, Giuseppe; Cammarota, Aldo.
In: Tumori, Vol. 102, No. 1, 01.01.2016, p. 71-76.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Diffusion-weighted magnetic resonance imaging in patients with prostate cancer treated with radiotherapy
AU - Iannelli, Giancarlo
AU - Caivano, Rocchina
AU - Rago, Luciana
AU - Simeon, Vittorio
AU - Lotumolo, Antonella
AU - Rabasco, Paola
AU - Villonio, Antonio
AU - Gioioso, Matilde
AU - Mastrangelo, Pietro
AU - Barchetti, Flavio
AU - Panebianco, Valeria
AU - Macarini, Luca
AU - Guglielmi, Giuseppe
AU - Cammarota, Aldo
PY - 2016/1/1
Y1 - 2016/1/1
N2 - Aims: To evaluate the utility of a multiparametric 3T magnetic resonance imaging (MRI) study using diffusion-weighted images (DWI) for the assessment of prostate cancer before and after radiotherapy (RT). Methods: A total of 34 patients, who received a histologic diagnosis of prostate adenocarcinoma, underwent MRI examination before and after local RT for the assessment of response to treatment. Apparent diffusion coefficient (ADC) values were calculated and compared. Results: Before RT, DWI shows pathologic restriction of signal, while after RT pathologic restriction of signal was reduced or disappeared. The ADC values were significantly increased after therapy (p
AB - Aims: To evaluate the utility of a multiparametric 3T magnetic resonance imaging (MRI) study using diffusion-weighted images (DWI) for the assessment of prostate cancer before and after radiotherapy (RT). Methods: A total of 34 patients, who received a histologic diagnosis of prostate adenocarcinoma, underwent MRI examination before and after local RT for the assessment of response to treatment. Apparent diffusion coefficient (ADC) values were calculated and compared. Results: Before RT, DWI shows pathologic restriction of signal, while after RT pathologic restriction of signal was reduced or disappeared. The ADC values were significantly increased after therapy (p
KW - Apparent diffusion coefficient
KW - Diffusion-weighed imaging
KW - Magnetic resonance imaging
KW - Prostate cancer
KW - Response to therapy
UR - http://www.scopus.com/inward/record.url?scp=84962822406&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84962822406&partnerID=8YFLogxK
U2 - 10.5301/tj.5000415
DO - 10.5301/tj.5000415
M3 - Article
VL - 102
SP - 71
EP - 76
JO - Tumori
JF - Tumori
SN - 0300-8916
IS - 1
ER -