Abstract
The aim of this study was to evaluate the capability and the reliability of diffusion-weighted MR imaging to differentiate benign from malignant renal lesions. Twenty healthy volunteers and 48 patients with known renal lesions underwent MR of the kidneys by using a 1.5 T superconductive magnet. Diffusion-weighted images (DWI) were obtained on the axial plane during breath-hold (17 s) with a SE EPI single shot sequence using a b value of 500 s/mm2. One region of interest (ROI) (lesions<than 3 cm) or 3 ROI (lesions > than 3 cm) were placed within the lesion for the measurement of apparent diffusion coefficient (ADC). ADC map was obtained at each slice position. Mean ADC value in normal renal parenchyma was 2.2± 0.20 × 10-3 mm2/s, while ADC values in simple cysts (n=20) were higher (mean ADC values 3.65±0.09 × 10-3 mm2/S). Solid benign and malignant renal tumors (n=19) showed a mean ADC value of 1.7±0.48 × 10-3 mm2/sec. The comparison between ADC values in normal parenchyma group and tumour group were found to be statistically significant (p
| Original language | English |
|---|---|
| Pages (from-to) | 39-45 |
| Number of pages | 7 |
| Journal | Journal of Experimental and Clinical Cancer Research |
| Volume | 23 |
| Issue number | 1 |
| Publication status | Published - Mar 2004 |
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Keywords
- Diffusion study
- Kidney
- Magnetic resonance (MR)
- Tumours
ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Diffusion-Weighted MR Imaging in the Evaluation of Renal Tumours. / Squillaci, Ettore; Manenti, G.; Di Stefano, F.; Miano, R.; Strigari, L.; Simonetti, G.
In: Journal of Experimental and Clinical Cancer Research, Vol. 23, No. 1, 03.2004, p. 39-45.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Diffusion-Weighted MR Imaging in the Evaluation of Renal Tumours
AU - Squillaci, Ettore
AU - Manenti, G.
AU - Di Stefano, F.
AU - Miano, R.
AU - Strigari, L.
AU - Simonetti, G.
PY - 2004/3
Y1 - 2004/3
N2 - The aim of this study was to evaluate the capability and the reliability of diffusion-weighted MR imaging to differentiate benign from malignant renal lesions. Twenty healthy volunteers and 48 patients with known renal lesions underwent MR of the kidneys by using a 1.5 T superconductive magnet. Diffusion-weighted images (DWI) were obtained on the axial plane during breath-hold (17 s) with a SE EPI single shot sequence using a b value of 500 s/mm2. One region of interest (ROI) (lesions than 3 cm) were placed within the lesion for the measurement of apparent diffusion coefficient (ADC). ADC map was obtained at each slice position. Mean ADC value in normal renal parenchyma was 2.2± 0.20 × 10-3 mm2/s, while ADC values in simple cysts (n=20) were higher (mean ADC values 3.65±0.09 × 10-3 mm2/S). Solid benign and malignant renal tumors (n=19) showed a mean ADC value of 1.7±0.48 × 10-3 mm2/sec. The comparison between ADC values in normal parenchyma group and tumour group were found to be statistically significant (p
AB - The aim of this study was to evaluate the capability and the reliability of diffusion-weighted MR imaging to differentiate benign from malignant renal lesions. Twenty healthy volunteers and 48 patients with known renal lesions underwent MR of the kidneys by using a 1.5 T superconductive magnet. Diffusion-weighted images (DWI) were obtained on the axial plane during breath-hold (17 s) with a SE EPI single shot sequence using a b value of 500 s/mm2. One region of interest (ROI) (lesions than 3 cm) were placed within the lesion for the measurement of apparent diffusion coefficient (ADC). ADC map was obtained at each slice position. Mean ADC value in normal renal parenchyma was 2.2± 0.20 × 10-3 mm2/s, while ADC values in simple cysts (n=20) were higher (mean ADC values 3.65±0.09 × 10-3 mm2/S). Solid benign and malignant renal tumors (n=19) showed a mean ADC value of 1.7±0.48 × 10-3 mm2/sec. The comparison between ADC values in normal parenchyma group and tumour group were found to be statistically significant (p
KW - Diffusion study
KW - Kidney
KW - Magnetic resonance (MR)
KW - Tumours
UR - http://www.scopus.com/inward/record.url?scp=2142698151&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=2142698151&partnerID=8YFLogxK
M3 - Article
C2 - 15149149
AN - SCOPUS:2142698151
VL - 23
SP - 39
EP - 45
JO - Journal of Experimental and Clinical Cancer Research
JF - Journal of Experimental and Clinical Cancer Research
SN - 0392-9078
IS - 1
ER -