Abstract
Purpose of investigation: Hydatidiform mole (HM) is an abnormal pregnancy characterized by proliferation of cytotrophoblast and syncytiotrophoblast and vesicular swelling of placental villi. The fetus or embryo can be absent or abnormal. HMs can be complete or partial. Case Report: A case of diginyc partial HM at 12 weeks of gestational age was referred to the present center of prenatal diagnosis. The patient showed ovarian hyperstimulation syndrome. At ultrasonography, increased fetal nuchal translucency (NT) with fetal anomaly was evident, without sonographic signs of placental mole. Pregnancy was terminated with legal abortion. Results: Partial HM (PHM) was suspected by ultrasonographic fetal markers with ovarian hyperstimulation syndrome, but the diagnosis was performed only with fluorescent in situ hybridization. In particular fetal NT appeared increased also in diginyc mole. Conclusion: In order to improve the detection rate of PHM, routine histological examinations may be associated to fluorescent in situ hybridization in all cases of fetal anomalies.
| Original language | English |
|---|---|
| Pages (from-to) | 467-469 |
| Number of pages | 3 |
| Journal | Clinical and Experimental Obstetrics and Gynecology |
| Volume | 43 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2016 |
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Keywords
- Diginyc mole
- Fetal nuchal translucency
- Ovarian hyperstimulation syndrome
- Partial hydatidiform mole
ASJC Scopus subject areas
- Obstetrics and Gynaecology
- Reproductive Medicine
Cite this
Diginyc partial hydatidiform mole with increased fetal nuchal translucency and ovarian hyperstimulation syndrome. / Gaggero, Chiara Roberta; Bogliolo, Stefano; Sala, Paolo; Molinari, C.; Motzo, S.; Fulcheri, Ezio; Anserini, Paola; De Biasio, Pierangela.
In: Clinical and Experimental Obstetrics and Gynecology, Vol. 43, No. 3, 2016, p. 467-469.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Diginyc partial hydatidiform mole with increased fetal nuchal translucency and ovarian hyperstimulation syndrome
AU - Gaggero, Chiara Roberta
AU - Bogliolo, Stefano
AU - Sala, Paolo
AU - Molinari, C.
AU - Motzo, S.
AU - Fulcheri, Ezio
AU - Anserini, Paola
AU - De Biasio, Pierangela
PY - 2016
Y1 - 2016
N2 - Purpose of investigation: Hydatidiform mole (HM) is an abnormal pregnancy characterized by proliferation of cytotrophoblast and syncytiotrophoblast and vesicular swelling of placental villi. The fetus or embryo can be absent or abnormal. HMs can be complete or partial. Case Report: A case of diginyc partial HM at 12 weeks of gestational age was referred to the present center of prenatal diagnosis. The patient showed ovarian hyperstimulation syndrome. At ultrasonography, increased fetal nuchal translucency (NT) with fetal anomaly was evident, without sonographic signs of placental mole. Pregnancy was terminated with legal abortion. Results: Partial HM (PHM) was suspected by ultrasonographic fetal markers with ovarian hyperstimulation syndrome, but the diagnosis was performed only with fluorescent in situ hybridization. In particular fetal NT appeared increased also in diginyc mole. Conclusion: In order to improve the detection rate of PHM, routine histological examinations may be associated to fluorescent in situ hybridization in all cases of fetal anomalies.
AB - Purpose of investigation: Hydatidiform mole (HM) is an abnormal pregnancy characterized by proliferation of cytotrophoblast and syncytiotrophoblast and vesicular swelling of placental villi. The fetus or embryo can be absent or abnormal. HMs can be complete or partial. Case Report: A case of diginyc partial HM at 12 weeks of gestational age was referred to the present center of prenatal diagnosis. The patient showed ovarian hyperstimulation syndrome. At ultrasonography, increased fetal nuchal translucency (NT) with fetal anomaly was evident, without sonographic signs of placental mole. Pregnancy was terminated with legal abortion. Results: Partial HM (PHM) was suspected by ultrasonographic fetal markers with ovarian hyperstimulation syndrome, but the diagnosis was performed only with fluorescent in situ hybridization. In particular fetal NT appeared increased also in diginyc mole. Conclusion: In order to improve the detection rate of PHM, routine histological examinations may be associated to fluorescent in situ hybridization in all cases of fetal anomalies.
KW - Diginyc mole
KW - Fetal nuchal translucency
KW - Ovarian hyperstimulation syndrome
KW - Partial hydatidiform mole
UR - http://www.scopus.com/inward/record.url?scp=84975090038&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84975090038&partnerID=8YFLogxK
U2 - 10.12891/ceog2160.2016
DO - 10.12891/ceog2160.2016
M3 - Article
VL - 43
SP - 467
EP - 469
JO - Clinical and Experimental Obstetrics and Gynecology
JF - Clinical and Experimental Obstetrics and Gynecology
SN - 0390-6663
IS - 3
ER -