Diode laser treatment of Barrett's esophagus: Long-term results

Lino Polese, Imerio Angriman, Marco Scarpa, Duilio Pagano, Paola Parente, Francesca Erroi, Mauro Frego, Davide F. D'Amico, Lorenzo Norberto

Research output: Contribution to journalArticlepeer-review

Abstract

Different ablation techniques have been utilized in the treatment of Barrett's esophagus (BE) to reduce the risk of degeneration. Treatment complications, risk of recurrence, and buried intestinal metaplasia (IM) are all major concerns. The effect of diode laser treatment on BE, studied in a group of patients over a long-term period, is presented here. All patients with histology of IM or low-grade dysplasia (LGD) treated with diode laser therapy for BE and followed for at least 24 months were included in the study. Treatment sessions were carried out every 3 months and bioptic follow-up examinations were done yearly. Patients without antireflux surgery received proton pump inhibitors. A total of 20 patients with IM, four of them with LGD, were treated with 161 laser sessions (in mean eight per patient) without complications. Complete, sustained endoscopic and histologic remission was obtained in 13 patients (11/12 with BE ≤ 3 cm and 2/8 with BE >3 cm, p

Original languageEnglish
Pages (from-to)223-228
Number of pages6
JournalLasers in Medical Science
Volume26
Issue number2
DOIs
Publication statusPublished - Mar 2011

Keywords

  • Ablation
  • Barrett's esophagus
  • Diode laser
  • Endoscopy
  • Intestinal metaplasia

ASJC Scopus subject areas

  • Surgery
  • Dermatology

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