Diogenes of Apollonia: A pioneer in vascular anatomy

Enrico Crivellato, Franco Mallardi, Domenico Ribatti

Research output: Contribution to journalArticlepeer-review


Diogenes of Apollonia was a pre-Socratic philosopher who lived in the 5th century BC and provided the first systematic and fairly truthful account of blood vessel architecture in man. This article presents Diogenes' report and comments on the most significant passages of his vascular description. It also discusses the magnitude of Diogenes' contribution to shape early theories regarding blood vessel physiology. What emerges from this portrait is the figure of an eclectic spirit, who remarkably influenced the development of leading concepts in vascular anatomy and biology.

Original languageEnglish
Pages (from-to)116-120
Number of pages5
JournalAnatomical Record - Part B New Anatomist
Issue number4
Publication statusPublished - Jul 2006


  • Anatomy
  • Blood vessels
  • Diogenes of Apollonia
  • Greek philosophy
  • History

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (miscellaneous)
  • Anatomy


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