The aim of this study was to assess the safety and prognostic value of dipyridamole-201Tl imaging very early after acute myocardial infarction in patients treated with thrombolytic therapy. Fifty-two consecutive patients with an uncomplicated clinical course underwent quantitative planar dipyridamole-201Tl imaging 2-5 days after acute myocardial infarction. The patients were followed for 14 ± 7 months after discharge. No major complications occurred during the test. Of the 30 patients with redistribution, five (16.6%) developed in-hospital unstable angina as against none of the 22 patients without redistribution. During follow-up, a total of five late cardiac events were observed: two deaths and two cases of unstable angina in the group with reversible defects and one reinfarction in the group with fixed defects. The 1-year actuarial probability of being free of cardiac events was, respectively, 66 ± 10% and 94 ± 5% in the patients with and without redistribution (P <0.01). In conclusion, in patients treated with thrombolysis, dipyridamole-201Tl imaging very early after uncomplicated acute myocardial infarction is a feasible and safe test. Patients with fixed defects appear to be at low risk and may be candidates for early discharge; the presence of redistribution identifies a subgroup of patients who may benefit from further careful clinical evaluation.
|Number of pages||6|
|Journal||European Heart Journal|
|Publication status||Published - 1997|
- Tl scintigraphy
- Acute myocardial infarction
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine