Direct detection of Helicobacter pylori mutations associated with macrolide resistance in gastric biopsy material taken from human immunodeficiency virus-infected subjects

Paolo Scarpellini, Paola Carrera, Annalisa Cavallero, Massimo Cernuschi, Gianni Mezzi, Pier Alberto Testoni, Anna Zingale, Adriano Lazzarin

Research output: Contribution to journalArticle

Abstract

One hundred forty gastric biopsies were tested by microbiological methods and by amplifying a sequence of 23S rRNA and identifying mutations associated to clarithromycin resistance. Seventy-six specimens were positive for Helicobacter pylori. Mutational analysis revealed alterations in 18 (39.1%) of 46 and 2 (8.7%) of 23 samples from human immunodeficiency virus-seropositive and -seronegative persons, respectively. The results of the mutational analysis fully correlated with those of the susceptibility tests.

Original languageEnglish
Pages (from-to)2234-2237
Number of pages4
JournalJournal of Clinical Microbiology
Volume40
Issue number6
DOIs
Publication statusPublished - 2002

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Fingerprint Dive into the research topics of 'Direct detection of Helicobacter pylori mutations associated with macrolide resistance in gastric biopsy material taken from human immunodeficiency virus-infected subjects'. Together they form a unique fingerprint.

  • Cite this