Disability in migraine patients: Italian experience

Gennaro Bussone, Licia Grazzi, Susanna Usai, Paola Mosconi, Sergio Genco, Franco Michele Puca, Domenico D'Amico

Research output: Contribution to journalArticlepeer-review


Migraine is associated with functional impairment. The migraine disability assessment (MIDAS) scale is a scientific instrument which captures headache-related disability. The Italian version of MIDAS was developed through a multi-step standardized methodology. Studies on Italian clinical samples showed that migraine patients were disabled in all activity domains. Non-work activities were more affected than work activities. Among patients in paid work, most continued working with a headache attack, although productivity was significantly reduced. The Italian MIDAS was used also in patients with transformed migraine and drug overuse. These patients were markedly disabled. MIDAS scores were higher than those found in migraine patients. When disability was assessed after 6 months from withdrawal therapy, MIDAS scores were significantly lower than at baseline. Our results confirmed the negative impact of the lives of headache patients, and suggest the use of MIDAS as a sensitive outcome measure for monitoring patients' progress.

Original languageEnglish
JournalJournal of Headache and Pain
Issue numberSUPPL. 1
Publication statusPublished - 2001


  • Disability
  • Migraine
  • Migraine disability assessment (MIDAS)
  • Outcome measure
  • Transformed migraine

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Neuroscience(all)


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