Disability in migraine without aura: The first italian study using the MIDAS questionnaire

D. D'Amico, D. Usai, S. Genco, A. M P Prudenzano, L. Grazzi, M. Leone, P. Mosconi, E. M. Puca, G. Bussone

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Epidemiological research has demonstrated that migraine sufferers report impairment in various activities. The Migraine Disability Assessment (MIDAS) questionnaire is a well-reported instrument designed to capture migraine-related disability, classifying patients into 4 progressive grades of disability. The definitive Italian version of MIDAS was recently developed by our group, after a previous pilot study. We demonstrated that this version is reliable, consistent, and suitable to be used as a clinical and research tool on Italian patients. The aim of the study was to assess disability in a population of migraine patients attending two Italian headache centres and to investigate the impact of migraine on different daily activities. One-hundred-ninety consecutive out-patients with IHS diagnosis of migraine without aura attending the headache centres of Milan and Bari entered the study (137 females, 53 males). They were invited to complete the MIDAS questionnaire, in order to evaluate the number of days with total or partial disability in different domains during the past 3 months. The mean MIDAS global score was 21.05 (median 16.5). Distribution of MIDAS disability grades was 16.3% grade I, 14.2% grade II, 27.9% grade III, and 41.6% grade IV. The mean and median scores at the individual MIDAS items were as follows: Item 1 (missed days for paid work or school), mean 1.96 (median 0); Item 2 (days with productivity at work or school reduced by half), 5.68 (4); Item 3 (missed days for household work), 4.55 (3); Item 4 (Days with productivity in household work reduced by half), 4.34 (3); and Item 5 (missed days for leisuresocial activities): 4.57 (3). The individual item scores were then calculated in the subgroup of patients who were on paid work, i.e. 138 (92 females, 46 males), and the results were as follows: mean MIDAS global score and 20.64 (median 16), item 1: mean 2.06 (median 0.5); Item 2: 6.31 (5); Item 3: 4.28 (3); Item 4: 3.90 (2.5) and item 5: 4.21 (3). Several studies showed an inability to carry out normal tasks in the workplace but also at home and at school in migraine patients. This is the first study to assess disability in a large sample of Italian migraine sufferers. Our results showed that most migraine patients attending a headache centre report a severe disability. Furthermore, analysis by activity domain revealed that these people are considerably more disabled in nonwork activities than in workplace activities. This is an important issue to be considered when addressing epidemiological research about per- sonal and social costs related to migraine.

Original languageEnglish
JournalNeurological Sciences
Issue number4 SUPPL.
Publication statusPublished - 2000

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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