During regeneration of rat livers following 70% hepatectomy, insulin binding sites on hepatocyte plasma membranes are increased after 24-48 hours, glucagon binding sites are reduced on days 2-8, and the resultant insulin/glucagon binding ratio is markedly increased. An apparent paradox was the finding of a depression of the activity of an insulin associated enzyme, glucokinase, at a time when the number of insulin binding sites was increased.
|Number of pages||4|
|Journal||Hormone and Metabolic Research|
|Issue number||SUPPL. 1|
|Publication status||Published - 1984|
ASJC Scopus subject areas