Abstract
During regeneration of rat livers following 70% hepatectomy, insulin binding sites on hepatocyte plasma membranes are increased after 24-48 hours, glucagon binding sites are reduced on days 2-8, and the resultant insulin/glucagon binding ratio is markedly increased. An apparent paradox was the finding of a depression of the activity of an insulin associated enzyme, glucokinase, at a time when the number of insulin binding sites was increased.
| Original language | English |
|---|---|
| Pages (from-to) | 47-50 |
| Number of pages | 4 |
| Journal | Hormone and Metabolic Research |
| Volume | 16 |
| Issue number | SUPPL. 1 |
| Publication status | Published - 1984 |
ASJC Scopus subject areas
- Biochemistry
- Endocrinology
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Francavilla, A., Di Leo, A., Wu, S. Q., Ove, P., Van Thiel, D., Sciascia, C., & Starzl, T. E. (1984). Discordance between glucokinase activity and insulin and glucagon receptor changes occurring during liver regeneration in the rat. Hormone and Metabolic Research, 16(SUPPL. 1), 47-50.