Discordant HHV8 detection in a young HIV-negative patient with Kaposi's sarcoma and sarcoidosis

G. Di Gennaro, V. Canzonieri, O. Schioppa, G. Nasti, A. Carbone, U. Tirelli

Research output: Contribution to journalArticle

Abstract

Human herpesvirus 8 (HHV8), which has been suggested as the causal agent of Kaposi's sarcoma (KS), has also been implicated in the pathogenesis of sarcoidosis. We describe a patient affected concomitantly by sarcoidosis and KS. HHV8 sequences were detected with PCR only on KS lesions, whereas sarcoid tissues did not harbor HHV8 DNA. Immune dysfunction related to sarcoidosis may have facilitated the oncogenic role of HHV8 and the development of KS.

Original languageEnglish
Pages (from-to)1100-1102
Number of pages3
JournalClinical Infectious Diseases
Volume32
Issue number7
DOIs
Publication statusPublished - Apr 1 2001

Fingerprint

Human Herpesvirus 8
Kaposi's Sarcoma
Sarcoidosis
HIV
Polymerase Chain Reaction
DNA

ASJC Scopus subject areas

  • Immunology

Cite this

Discordant HHV8 detection in a young HIV-negative patient with Kaposi's sarcoma and sarcoidosis. / Di Gennaro, G.; Canzonieri, V.; Schioppa, O.; Nasti, G.; Carbone, A.; Tirelli, U.

In: Clinical Infectious Diseases, Vol. 32, No. 7, 01.04.2001, p. 1100-1102.

Research output: Contribution to journalArticle

Di Gennaro, G. ; Canzonieri, V. ; Schioppa, O. ; Nasti, G. ; Carbone, A. ; Tirelli, U. / Discordant HHV8 detection in a young HIV-negative patient with Kaposi's sarcoma and sarcoidosis. In: Clinical Infectious Diseases. 2001 ; Vol. 32, No. 7. pp. 1100-1102.
@article{db96115abb304e9ba8142ebb6aea9bb3,
title = "Discordant HHV8 detection in a young HIV-negative patient with Kaposi's sarcoma and sarcoidosis",
abstract = "Human herpesvirus 8 (HHV8), which has been suggested as the causal agent of Kaposi's sarcoma (KS), has also been implicated in the pathogenesis of sarcoidosis. We describe a patient affected concomitantly by sarcoidosis and KS. HHV8 sequences were detected with PCR only on KS lesions, whereas sarcoid tissues did not harbor HHV8 DNA. Immune dysfunction related to sarcoidosis may have facilitated the oncogenic role of HHV8 and the development of KS.",
author = "{Di Gennaro}, G. and V. Canzonieri and O. Schioppa and G. Nasti and A. Carbone and U. Tirelli",
year = "2001",
month = "4",
day = "1",
doi = "10.1086/319603",
language = "English",
volume = "32",
pages = "1100--1102",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "NLM (Medline)",
number = "7",

}

TY - JOUR

T1 - Discordant HHV8 detection in a young HIV-negative patient with Kaposi's sarcoma and sarcoidosis

AU - Di Gennaro, G.

AU - Canzonieri, V.

AU - Schioppa, O.

AU - Nasti, G.

AU - Carbone, A.

AU - Tirelli, U.

PY - 2001/4/1

Y1 - 2001/4/1

N2 - Human herpesvirus 8 (HHV8), which has been suggested as the causal agent of Kaposi's sarcoma (KS), has also been implicated in the pathogenesis of sarcoidosis. We describe a patient affected concomitantly by sarcoidosis and KS. HHV8 sequences were detected with PCR only on KS lesions, whereas sarcoid tissues did not harbor HHV8 DNA. Immune dysfunction related to sarcoidosis may have facilitated the oncogenic role of HHV8 and the development of KS.

AB - Human herpesvirus 8 (HHV8), which has been suggested as the causal agent of Kaposi's sarcoma (KS), has also been implicated in the pathogenesis of sarcoidosis. We describe a patient affected concomitantly by sarcoidosis and KS. HHV8 sequences were detected with PCR only on KS lesions, whereas sarcoid tissues did not harbor HHV8 DNA. Immune dysfunction related to sarcoidosis may have facilitated the oncogenic role of HHV8 and the development of KS.

UR - http://www.scopus.com/inward/record.url?scp=0035310498&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035310498&partnerID=8YFLogxK

U2 - 10.1086/319603

DO - 10.1086/319603

M3 - Article

C2 - 11264040

AN - SCOPUS:0035310498

VL - 32

SP - 1100

EP - 1102

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

IS - 7

ER -