Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study

Scott L. Weiss, Julie C. Fitzgerald, Frank A. Maffei, Jason M. Kane, Antonio Rodriguez-Nunez, Deyin D. Hsing, Deborah Franzon, Sze Ying Kee, Jenny L. Bush, Jason A. Roy, Neal J. Thomas, Vinay M. Nadkarni, P. Fontela, M. Tucci, M. Dumistrascu, P. Skippen, G. Krahn, E. Bezares, G. Puig, A. Puig-RamosR. Garcia, M. Villar, M. Bigham, T. Polanski, S. Latifi, D. Giebner, H. Anthony, J. Hume, A. Galster, L. Linnerud, R. Sanders, G. Hefley, K. Madden, A. Thompson, S. Shein, S. Gertz, Y. Han, T. Williams, A. Hughes-Schalk, H. Chandler, A. Orioles, E. Zielinski, A. Doucette, A. Orioles, E. Zielinski, A. Doucette, M. Di Nardo, S. Picardo, T. Fragasso, P. Cogo, for the SPROUT Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

Introduction: Consensus criteria for pediatric severe sepsis have standardized enrollment for research studies. However, the extent to which critically ill children identified by consensus criteria reflect physician diagnosis of severe sepsis, which underlies external validity for pediatric sepsis research, is not known. We sought to determine the agreement between physician diagnosis and consensus criteria to identify pediatric patients with severe sepsis across a network of international pediatric intensive care units (PICUs). Methods: We conducted a point prevalence study involving 128 PICUs in 26 countries across 6 continents. Over the course of 5 study days, 6925 PICU patients

Original languageEnglish
Article number325
JournalCritical Care
Volume19
Issue number1
DOIs
Publication statusPublished - Sep 16 2015

Fingerprint

Pediatric Intensive Care Units
Sepsis
Cross-Sectional Studies
Pediatrics
Research
Physicians
Critical Illness

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Weiss, S. L., Fitzgerald, J. C., Maffei, F. A., Kane, J. M., Rodriguez-Nunez, A., Hsing, D. D., ... for the SPROUT Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network (2015). Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study. Critical Care, 19(1), [325]. https://doi.org/10.1186/s13054-015-1055-x

Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study. / Weiss, Scott L.; Fitzgerald, Julie C.; Maffei, Frank A.; Kane, Jason M.; Rodriguez-Nunez, Antonio; Hsing, Deyin D.; Franzon, Deborah; Kee, Sze Ying; Bush, Jenny L.; Roy, Jason A.; Thomas, Neal J.; Nadkarni, Vinay M.; Fontela, P.; Tucci, M.; Dumistrascu, M.; Skippen, P.; Krahn, G.; Bezares, E.; Puig, G.; Puig-Ramos, A.; Garcia, R.; Villar, M.; Bigham, M.; Polanski, T.; Latifi, S.; Giebner, D.; Anthony, H.; Hume, J.; Galster, A.; Linnerud, L.; Sanders, R.; Hefley, G.; Madden, K.; Thompson, A.; Shein, S.; Gertz, S.; Han, Y.; Williams, T.; Hughes-Schalk, A.; Chandler, H.; Orioles, A.; Zielinski, E.; Doucette, A.; Orioles, A.; Zielinski, E.; Doucette, A.; Di Nardo, M.; Picardo, S.; Fragasso, T.; Cogo, P.; for the SPROUT Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network.

In: Critical Care, Vol. 19, No. 1, 325, 16.09.2015.

Research output: Contribution to journalArticle

Weiss, SL, Fitzgerald, JC, Maffei, FA, Kane, JM, Rodriguez-Nunez, A, Hsing, DD, Franzon, D, Kee, SY, Bush, JL, Roy, JA, Thomas, NJ, Nadkarni, VM, Fontela, P, Tucci, M, Dumistrascu, M, Skippen, P, Krahn, G, Bezares, E, Puig, G, Puig-Ramos, A, Garcia, R, Villar, M, Bigham, M, Polanski, T, Latifi, S, Giebner, D, Anthony, H, Hume, J, Galster, A, Linnerud, L, Sanders, R, Hefley, G, Madden, K, Thompson, A, Shein, S, Gertz, S, Han, Y, Williams, T, Hughes-Schalk, A, Chandler, H, Orioles, A, Zielinski, E, Doucette, A, Orioles, A, Zielinski, E, Doucette, A, Di Nardo, M, Picardo, S, Fragasso, T, Cogo, P & for the SPROUT Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network 2015, 'Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study', Critical Care, vol. 19, no. 1, 325. https://doi.org/10.1186/s13054-015-1055-x
Weiss, Scott L. ; Fitzgerald, Julie C. ; Maffei, Frank A. ; Kane, Jason M. ; Rodriguez-Nunez, Antonio ; Hsing, Deyin D. ; Franzon, Deborah ; Kee, Sze Ying ; Bush, Jenny L. ; Roy, Jason A. ; Thomas, Neal J. ; Nadkarni, Vinay M. ; Fontela, P. ; Tucci, M. ; Dumistrascu, M. ; Skippen, P. ; Krahn, G. ; Bezares, E. ; Puig, G. ; Puig-Ramos, A. ; Garcia, R. ; Villar, M. ; Bigham, M. ; Polanski, T. ; Latifi, S. ; Giebner, D. ; Anthony, H. ; Hume, J. ; Galster, A. ; Linnerud, L. ; Sanders, R. ; Hefley, G. ; Madden, K. ; Thompson, A. ; Shein, S. ; Gertz, S. ; Han, Y. ; Williams, T. ; Hughes-Schalk, A. ; Chandler, H. ; Orioles, A. ; Zielinski, E. ; Doucette, A. ; Orioles, A. ; Zielinski, E. ; Doucette, A. ; Di Nardo, M. ; Picardo, S. ; Fragasso, T. ; Cogo, P. ; for the SPROUT Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network. / Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study. In: Critical Care. 2015 ; Vol. 19, No. 1.
@article{d704f1a57f4a443ab4a37163e76772cf,
title = "Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study",
abstract = "Introduction: Consensus criteria for pediatric severe sepsis have standardized enrollment for research studies. However, the extent to which critically ill children identified by consensus criteria reflect physician diagnosis of severe sepsis, which underlies external validity for pediatric sepsis research, is not known. We sought to determine the agreement between physician diagnosis and consensus criteria to identify pediatric patients with severe sepsis across a network of international pediatric intensive care units (PICUs). Methods: We conducted a point prevalence study involving 128 PICUs in 26 countries across 6 continents. Over the course of 5 study days, 6925 PICU patients",
author = "Weiss, {Scott L.} and Fitzgerald, {Julie C.} and Maffei, {Frank A.} and Kane, {Jason M.} and Antonio Rodriguez-Nunez and Hsing, {Deyin D.} and Deborah Franzon and Kee, {Sze Ying} and Bush, {Jenny L.} and Roy, {Jason A.} and Thomas, {Neal J.} and Nadkarni, {Vinay M.} and P. Fontela and M. Tucci and M. Dumistrascu and P. Skippen and G. Krahn and E. Bezares and G. Puig and A. Puig-Ramos and R. Garcia and M. Villar and M. Bigham and T. Polanski and S. Latifi and D. Giebner and H. Anthony and J. Hume and A. Galster and L. Linnerud and R. Sanders and G. Hefley and K. Madden and A. Thompson and S. Shein and S. Gertz and Y. Han and T. Williams and A. Hughes-Schalk and H. Chandler and A. Orioles and E. Zielinski and A. Doucette and A. Orioles and E. Zielinski and A. Doucette and {Di Nardo}, M. and S. Picardo and T. Fragasso and P. Cogo and {for the SPROUT Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network}",
year = "2015",
month = "9",
day = "16",
doi = "10.1186/s13054-015-1055-x",
language = "English",
volume = "19",
journal = "Critical Care",
issn = "1466-609X",
publisher = "Springer Science + Business Media",
number = "1",

}

TY - JOUR

T1 - Discordant identification of pediatric severe sepsis by research and clinical definitions in the SPROUT international point prevalence study

AU - Weiss, Scott L.

AU - Fitzgerald, Julie C.

AU - Maffei, Frank A.

AU - Kane, Jason M.

AU - Rodriguez-Nunez, Antonio

AU - Hsing, Deyin D.

AU - Franzon, Deborah

AU - Kee, Sze Ying

AU - Bush, Jenny L.

AU - Roy, Jason A.

AU - Thomas, Neal J.

AU - Nadkarni, Vinay M.

AU - Fontela, P.

AU - Tucci, M.

AU - Dumistrascu, M.

AU - Skippen, P.

AU - Krahn, G.

AU - Bezares, E.

AU - Puig, G.

AU - Puig-Ramos, A.

AU - Garcia, R.

AU - Villar, M.

AU - Bigham, M.

AU - Polanski, T.

AU - Latifi, S.

AU - Giebner, D.

AU - Anthony, H.

AU - Hume, J.

AU - Galster, A.

AU - Linnerud, L.

AU - Sanders, R.

AU - Hefley, G.

AU - Madden, K.

AU - Thompson, A.

AU - Shein, S.

AU - Gertz, S.

AU - Han, Y.

AU - Williams, T.

AU - Hughes-Schalk, A.

AU - Chandler, H.

AU - Orioles, A.

AU - Zielinski, E.

AU - Doucette, A.

AU - Orioles, A.

AU - Zielinski, E.

AU - Doucette, A.

AU - Di Nardo, M.

AU - Picardo, S.

AU - Fragasso, T.

AU - Cogo, P.

AU - for the SPROUT Study Investigators and Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network

PY - 2015/9/16

Y1 - 2015/9/16

N2 - Introduction: Consensus criteria for pediatric severe sepsis have standardized enrollment for research studies. However, the extent to which critically ill children identified by consensus criteria reflect physician diagnosis of severe sepsis, which underlies external validity for pediatric sepsis research, is not known. We sought to determine the agreement between physician diagnosis and consensus criteria to identify pediatric patients with severe sepsis across a network of international pediatric intensive care units (PICUs). Methods: We conducted a point prevalence study involving 128 PICUs in 26 countries across 6 continents. Over the course of 5 study days, 6925 PICU patients

AB - Introduction: Consensus criteria for pediatric severe sepsis have standardized enrollment for research studies. However, the extent to which critically ill children identified by consensus criteria reflect physician diagnosis of severe sepsis, which underlies external validity for pediatric sepsis research, is not known. We sought to determine the agreement between physician diagnosis and consensus criteria to identify pediatric patients with severe sepsis across a network of international pediatric intensive care units (PICUs). Methods: We conducted a point prevalence study involving 128 PICUs in 26 countries across 6 continents. Over the course of 5 study days, 6925 PICU patients

UR - http://www.scopus.com/inward/record.url?scp=84941957349&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84941957349&partnerID=8YFLogxK

U2 - 10.1186/s13054-015-1055-x

DO - 10.1186/s13054-015-1055-x

M3 - Article

AN - SCOPUS:84941957349

VL - 19

JO - Critical Care

JF - Critical Care

SN - 1466-609X

IS - 1

M1 - 325

ER -