Discriminant analysis of beck depression inventory and hamilton rating scale for depression in huntington's disease

Hugh Rickards, Jennifer de Souza, Jennifer Crooks, Marleen R. van Walsem, Erik van Duijn, Bernhard Landwehrmeyer, Ferdinando Squitieri, Sheila A. Simpson

Research output: Contribution to journalArticle

Abstract

Depression is common in Huntington's disease, but standard rating scales have doubtful validity in this population. Using data from the European Huntington's Disease REGISTRY study, the authors examined the discriminant value of items on the Beck Depression Inventory (N=843) and the Hamilton Rating Scale for Depression (N=768). Good discriminators of depression, apart from "depressed mood," were "guilt," "loss of interest," and "suicidality" Items that discriminated poorly were "weight loss," "sleep disturbance," "loss of appetite," "psychomotor retardation," "agitation," and "irritability." These findings highlight the limited usefulness of these scales within the area of Huntington's disease.

Original languageEnglish
Pages (from-to)399-402
Number of pages4
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume23
Issue number4
Publication statusPublished - 2011

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Neurology

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