Disease-related malnutrition in systemic sclerosis: Evidences and implications

Research output: Contribution to journalArticle

Abstract

The present review summarises evidences and provides recommendations for the screening and management of malnutrition in systemic sclerosis (SSc). This complication is frequently underestimated when assessing patients and this may lead to an impaired estimation of prognosis. The presence of malnutrition is indicated by anthropometric and biohumoral changes reflecting protein stores (low serum prealbumin) and influenced by organ involvement in SSc (skin and the gastrointestinal tract). Patients at high risk of malnutrition or with low prealbumin levels have shown increased mortality risk and, therefore, a nutritional assessment is mandatory in every SSc patient. This screening is especially important as malnutrition represents a potentially modifiable risk factor with nutritional interventions. The pillars of nutritional treatment are also discussed.

Original languageEnglish
Pages (from-to)190-194
Number of pages5
JournalClinical and Experimental Rheumatology
Volume33
Publication statusPublished - 2015

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Systemic Scleroderma
Malnutrition
Prealbumin
Nutrition Assessment
Gastrointestinal Tract
Skin
Mortality
Serum
Proteins
Therapeutics

Keywords

  • Malnutrition
  • Malnutrition universal screening tool
  • Prealbumin
  • Systemic sclerosis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy
  • Medicine(all)

Cite this

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title = "Disease-related malnutrition in systemic sclerosis: Evidences and implications",
abstract = "The present review summarises evidences and provides recommendations for the screening and management of malnutrition in systemic sclerosis (SSc). This complication is frequently underestimated when assessing patients and this may lead to an impaired estimation of prognosis. The presence of malnutrition is indicated by anthropometric and biohumoral changes reflecting protein stores (low serum prealbumin) and influenced by organ involvement in SSc (skin and the gastrointestinal tract). Patients at high risk of malnutrition or with low prealbumin levels have shown increased mortality risk and, therefore, a nutritional assessment is mandatory in every SSc patient. This screening is especially important as malnutrition represents a potentially modifiable risk factor with nutritional interventions. The pillars of nutritional treatment are also discussed.",
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AU - Codullo, Veronica

AU - Cereda, Emanuele

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AU - Cappello, Silvia

AU - Montecucco, Carlomaurizio

AU - Caccialanza, Riccardo

AU - Caporali, Roberto

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AB - The present review summarises evidences and provides recommendations for the screening and management of malnutrition in systemic sclerosis (SSc). This complication is frequently underestimated when assessing patients and this may lead to an impaired estimation of prognosis. The presence of malnutrition is indicated by anthropometric and biohumoral changes reflecting protein stores (low serum prealbumin) and influenced by organ involvement in SSc (skin and the gastrointestinal tract). Patients at high risk of malnutrition or with low prealbumin levels have shown increased mortality risk and, therefore, a nutritional assessment is mandatory in every SSc patient. This screening is especially important as malnutrition represents a potentially modifiable risk factor with nutritional interventions. The pillars of nutritional treatment are also discussed.

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