TY - JOUR
T1 - Dislipidemia e terapia ipolipemizzante
T2 - Dalle linee guida alla pratica clinica Una rassegna aggiornata della letteratura
AU - Lucchi, Tiziano
AU - Cesari, Matteo
AU - Vergani, Carlo
PY - 2020/8
Y1 - 2020/8
N2 - The atherosclerotic cardiovascular disease (ASCVD) represents the leading cause of death and disability not only in countries with a high degree of socio-economic development but also in low-middle-income countries. The study of atherosclerosis and the strategies to control ASCVD are evolving. All strategies emphasize the need to lower LDL cholesterol through an appropriate lifestyle and the use of lipid-lowering drugs. A therapy with statin with or without other lipid lowering drugs is recommended in secondary prevention. In primary prevention, the use of the lipid-lowering drug should instead take into account the cost-benefit ratio. Available evidence coming from clinical trials is useful to inform clinical choices but must be associated with a shared decision-making process between doctor and patient.
AB - The atherosclerotic cardiovascular disease (ASCVD) represents the leading cause of death and disability not only in countries with a high degree of socio-economic development but also in low-middle-income countries. The study of atherosclerosis and the strategies to control ASCVD are evolving. All strategies emphasize the need to lower LDL cholesterol through an appropriate lifestyle and the use of lipid-lowering drugs. A therapy with statin with or without other lipid lowering drugs is recommended in secondary prevention. In primary prevention, the use of the lipid-lowering drug should instead take into account the cost-benefit ratio. Available evidence coming from clinical trials is useful to inform clinical choices but must be associated with a shared decision-making process between doctor and patient.
KW - Atherosclerosis
KW - Dyslipidemia
KW - Hypercholesterolemia
KW - Lipid lowering drugs
KW - Statins
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U2 - 10.1701/3407.33925
DO - 10.1701/3407.33925
M3 - Articolo
C2 - 32658882
AN - SCOPUS:85088030143
VL - 111
SP - 426
EP - 443
JO - Recenti Progressi in Medicina
JF - Recenti Progressi in Medicina
SN - 0034-1193
IS - 7
ER -