TY - JOUR
T1 - Dissecting a Hub for Immune Response
T2 - Modeling the Structure of MyD88
AU - Naro, Chiara
AU - Sette, Claudio
PY - 2016/3/1
Y1 - 2016/3/1
N2 - Immune cells sense foreign organisms through the evolutionarily conserved family of Toll-like receptors. Signaling from these receptors relies on oligomerization of adaptor molecules. In this issue of Structure, Vynke et al. (2016) shed light on the dynamical structure of the homo- and hetero-dimerization domain of MyD88, the main adaptor utilized by Toll-like receptors.
AB - Immune cells sense foreign organisms through the evolutionarily conserved family of Toll-like receptors. Signaling from these receptors relies on oligomerization of adaptor molecules. In this issue of Structure, Vynke et al. (2016) shed light on the dynamical structure of the homo- and hetero-dimerization domain of MyD88, the main adaptor utilized by Toll-like receptors.
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U2 - 10.1016/j.str.2016.02.005
DO - 10.1016/j.str.2016.02.005
M3 - Article
C2 - 26933969
AN - SCOPUS:84959348449
VL - 24
SP - 349
EP - 351
JO - Structure with Folding & design
JF - Structure with Folding & design
SN - 0969-2126
IS - 3
ER -