Dissecting a Hub for Immune Response: Modeling the Structure of MyD88

Chiara Naro, Claudio Sette

Research output: Contribution to journalArticlepeer-review

Abstract

Immune cells sense foreign organisms through the evolutionarily conserved family of Toll-like receptors. Signaling from these receptors relies on oligomerization of adaptor molecules. In this issue of Structure, Vynke et al. (2016) shed light on the dynamical structure of the homo- and hetero-dimerization domain of MyD88, the main adaptor utilized by Toll-like receptors.

Original languageEnglish
Pages (from-to)349-351
Number of pages3
JournalStructure
Volume24
Issue number3
DOIs
Publication statusPublished - Mar 1 2016

ASJC Scopus subject areas

  • Molecular Biology
  • Structural Biology

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