Disseminated autoimmune disease during levamisole treatment of nephrotic syndrome

Giancarlo Barbano, Fabrizio Ginevri, Gian M. Ghiggeri, Rosanna Gusmano

Research output: Contribution to journalArticlepeer-review

Abstract

Side effects such as cutaneous vasculitis, which occur during prolonged levamisole treatment, may discourage the utilization of the drug in relapsing nephrotic syndrome. We describe a child who developed disseminated vasculitis during prolonged treatment with levamisole. The acute phase was characterized by hepatosplenomegaly, hemolytic anemia, IgM anticardiolipin and p-antineutrophil cytoplasmic antibodies. One month after withdrawal of therapy all symptoms had disappeared and tests normalized. This case report, together with other reports on cutaneous vasculitis, suggest caution and close monitoring during prolonged levamisole therapy.

Original languageEnglish
Pages (from-to)602-603
Number of pages2
JournalPediatric Nephrology
Volume13
Issue number7
DOIs
Publication statusPublished - Sep 1999

Keywords

  • Levamisole
  • Nephrotic syndrome
  • Vasculitis

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

Fingerprint Dive into the research topics of 'Disseminated autoimmune disease during levamisole treatment of nephrotic syndrome'. Together they form a unique fingerprint.

Cite this