Disseminated intravascular coagulation and severe peripheral neuropathy complicating ketoacidosis in a newly diagnosed diabetic child

R. Bonfanti, E. Bognetti, F. Meschi, S. Medaglini, A. D'Angelo, G. Chiumello

Research output: Contribution to journalArticle

Abstract

Disseminated intravascular coagulation is a very rare complication of diabetic ketoacidosis. Central nervous system plasy but not peripheral neuropathy has been reported in these patients. On the other hand, signs of peripheral neuropathy may also be present at the onset of diabetes, but they are usually reversible within a few days after correction of the metabolic derangement. We describe an unusual case of mononeuritis multiplex syndrome still present after 2 months of follow-up in a child with diabetic ketoacidosis complicated by disseminated intravascular coagulation at the onset of insulin-dependent diabetes. These neurological impairments may be consistent with functional neural lesions due to vasa nervorum thrombosis and prolonged ischaemia.

Original languageEnglish
Pages (from-to)173-174
Number of pages2
JournalActa Diabetologica
Volume31
Issue number3
DOIs
Publication statusPublished - Sep 1994

Fingerprint

Diabetic Ketoacidosis
Ketosis
Disseminated Intravascular Coagulation
Peripheral Nervous System Diseases
Vasa Nervorum
Mononeuropathies
Thrombosis
Ischemia
Central Nervous System
Insulin

Keywords

  • Childhood diabetes
  • Diabetic ketoacidosis
  • Disseminated intravascular coagulation
  • Peripheral neuropathy

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

Cite this

Disseminated intravascular coagulation and severe peripheral neuropathy complicating ketoacidosis in a newly diagnosed diabetic child. / Bonfanti, R.; Bognetti, E.; Meschi, F.; Medaglini, S.; D'Angelo, A.; Chiumello, G.

In: Acta Diabetologica, Vol. 31, No. 3, 09.1994, p. 173-174.

Research output: Contribution to journalArticle

@article{cce67b20e70148ed9f720bedd6be4fa3,
title = "Disseminated intravascular coagulation and severe peripheral neuropathy complicating ketoacidosis in a newly diagnosed diabetic child",
abstract = "Disseminated intravascular coagulation is a very rare complication of diabetic ketoacidosis. Central nervous system plasy but not peripheral neuropathy has been reported in these patients. On the other hand, signs of peripheral neuropathy may also be present at the onset of diabetes, but they are usually reversible within a few days after correction of the metabolic derangement. We describe an unusual case of mononeuritis multiplex syndrome still present after 2 months of follow-up in a child with diabetic ketoacidosis complicated by disseminated intravascular coagulation at the onset of insulin-dependent diabetes. These neurological impairments may be consistent with functional neural lesions due to vasa nervorum thrombosis and prolonged ischaemia.",
keywords = "Childhood diabetes, Diabetic ketoacidosis, Disseminated intravascular coagulation, Peripheral neuropathy",
author = "R. Bonfanti and E. Bognetti and F. Meschi and S. Medaglini and A. D'Angelo and G. Chiumello",
year = "1994",
month = "9",
doi = "10.1007/BF00570376",
language = "English",
volume = "31",
pages = "173--174",
journal = "Acta Diabetologica",
issn = "0940-5429",
publisher = "Springer-Verlag Italia s.r.l.",
number = "3",

}

TY - JOUR

T1 - Disseminated intravascular coagulation and severe peripheral neuropathy complicating ketoacidosis in a newly diagnosed diabetic child

AU - Bonfanti, R.

AU - Bognetti, E.

AU - Meschi, F.

AU - Medaglini, S.

AU - D'Angelo, A.

AU - Chiumello, G.

PY - 1994/9

Y1 - 1994/9

N2 - Disseminated intravascular coagulation is a very rare complication of diabetic ketoacidosis. Central nervous system plasy but not peripheral neuropathy has been reported in these patients. On the other hand, signs of peripheral neuropathy may also be present at the onset of diabetes, but they are usually reversible within a few days after correction of the metabolic derangement. We describe an unusual case of mononeuritis multiplex syndrome still present after 2 months of follow-up in a child with diabetic ketoacidosis complicated by disseminated intravascular coagulation at the onset of insulin-dependent diabetes. These neurological impairments may be consistent with functional neural lesions due to vasa nervorum thrombosis and prolonged ischaemia.

AB - Disseminated intravascular coagulation is a very rare complication of diabetic ketoacidosis. Central nervous system plasy but not peripheral neuropathy has been reported in these patients. On the other hand, signs of peripheral neuropathy may also be present at the onset of diabetes, but they are usually reversible within a few days after correction of the metabolic derangement. We describe an unusual case of mononeuritis multiplex syndrome still present after 2 months of follow-up in a child with diabetic ketoacidosis complicated by disseminated intravascular coagulation at the onset of insulin-dependent diabetes. These neurological impairments may be consistent with functional neural lesions due to vasa nervorum thrombosis and prolonged ischaemia.

KW - Childhood diabetes

KW - Diabetic ketoacidosis

KW - Disseminated intravascular coagulation

KW - Peripheral neuropathy

UR - http://www.scopus.com/inward/record.url?scp=0028094803&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028094803&partnerID=8YFLogxK

U2 - 10.1007/BF00570376

DO - 10.1007/BF00570376

M3 - Article

C2 - 7827359

AN - SCOPUS:0028094803

VL - 31

SP - 173

EP - 174

JO - Acta Diabetologica

JF - Acta Diabetologica

SN - 0940-5429

IS - 3

ER -