Dissociated local arousal states underlying essential clinical features of non-rapid eye movement arousal parasomnia: An intracerebral stereo-electroencephalographic study

Michele Terzaghi, Ivana Sartori, Laura Tassi, Valter Rustioni, Paola Proserpio, Giorgio Lorusso, Raffaele Manni, Lino Nobili

Research output: Contribution to journalArticle

Abstract

Sleep has been shown to be a global phenomenon in which the presence of local processes of both activation and deactivation are finely orchestrated. Dysfunctional and independent action of the systems involved in non-rapid eye movement (NREM) sleep and wakefulness is deemed to be at the basis of arousal parasomnias. We show, in a patient with confusional arousals, persistence of sleep in the hippocampal and frontal associative cortices in contrast to the presence of awakening in the motor, cingulate, insular, amygdalar and temporopolar cortices. The clinical features of the confusional arousals in this patient are highly consistent with a dysfunctional coexistence of local cortical arousal and local cortical sleep.

Original languageEnglish
Pages (from-to)502-506
Number of pages5
JournalJournal of Sleep Research
Volume21
Issue number5
DOIs
Publication statusPublished - Oct 2012

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Keywords

  • Confusional arousal
  • Local arousal
  • NREM parasomnia
  • State dissociation
  • Stereo-EEG

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Medicine(all)

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