DISSOLUTION DES CALCULS BILIAIRES DE CHOLESTEROL PAR L'ACIDE CHENODESOXYCHOLIQUE

Translated title of the contribution: Dissolution of cholesterol biliary calculi by chenodesoxycholic acid

G. Celle, G. Ciravegna, V. Deconca, C. Mansi, A. Picciotto, V. Savarino, M. Dodero

Research output: Contribution to journalArticle

Abstract

The authors present their results in the treatment of gall stones by means of chenodesoxycholic acid (CDCA). The study concerns 103 patients: 100 of whom presented stones in the gall bladder, 3 presented stones in the main bile duct. All these patients have correctly carried out the treatment for 6 months at least and the percentage of partial or total dissolution was calculated, dividing them into 2 groups according to the doses of CDCA they have taken: the rate of success was 67.3% in the 52 patients who have taken 15 mg/Kg/day; while in the 29 patients who have taken 8-10 mg/Kg/day, the percentage was 34.4%. In 11 patients of this second group, who have increased the doses to 15 mg/Kg/day, there was a favourable response in 7 cases (63.6%). Dissolution has also been obtained in the 3 cases of stones in the biliary tree.

Translated title of the contributionDissolution of cholesterol biliary calculi by chenodesoxycholic acid
Original languageFrench
Pages (from-to)321-324
Number of pages4
JournalMedecine et Chirurgie Digestives
Volume7
Issue number4
Publication statusPublished - 1978

ASJC Scopus subject areas

  • Gastroenterology
  • Surgery

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    Celle, G., Ciravegna, G., Deconca, V., Mansi, C., Picciotto, A., Savarino, V., & Dodero, M. (1978). DISSOLUTION DES CALCULS BILIAIRES DE CHOLESTEROL PAR L'ACIDE CHENODESOXYCHOLIQUE. Medecine et Chirurgie Digestives, 7(4), 321-324.