Distinctive clinical features of pediatric systemic lupus erythematosus in three different age classes

F. R. Pluchinotta, B. Schiavo, F. Vittadello, G. Martini, G. Perilongo, Francesco Zulian

Research output: Contribution to journalArticlepeer-review

Abstract

It is estimated that around 20% of patients with systemic lupus erythematosus (SLE) have their onset in childhood but there have been conflicting data about the prevalence and severity of the clinical features in different age classes. We conducted this study to analyse the clinical features of patients with pediatric SLE (pSLE) with onset in infancy, prepubertal and postpubertal age. The charts of patients followed at the Department of Pediatrics, University of Padua, who met the criteria for SLE diagnosis, were reviewed. Patients were divided into three groups based on age at disease onset: group A, patients ≤2 years old, group B patients aged between 2 and 10 years, group C patients between 11 and 16 years of age. The clinical and laboratory characteristics of each group were compared. Forty-two patients with pSLE entered the study: 2 were diagnosed before the age of 2 years, 11 between 2 and 10 years and 29 between 10 and 16 years. Eleven more patients with infantile (onset

Original languageEnglish
Pages (from-to)550-555
Number of pages6
JournalLupus
Volume16
Issue number8
DOIs
Publication statusPublished - 2007

Keywords

  • Child
  • Infant
  • Outcome
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology
  • Immunology

Fingerprint Dive into the research topics of 'Distinctive clinical features of pediatric systemic lupus erythematosus in three different age classes'. Together they form a unique fingerprint.

Cite this