The bombesin group of hormonal peptides produced in the amphibian skin have powerful actions on the mammalian gastrointestinal tract. In man a bombesin like material was found in an endocrine cell which is widely distributed in the gastrointestinal mucosa. This has tentatively been identified as belonging to the non enterochromaffin cell groups. The large number of cells containing a bombesin like peptide suggests that this substance may be important in human physiology.
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