Distribution of forensic marker allelic frequencies in pernambuco, Northestern Brazil

S. M. Santos, C. A. Souza, K. C N Rabelo, P. Souza, R. R. Moura, T. C. Oliveira, S. Crovella

Research output: Contribution to journalArticle

Abstract

Pernambuco is one of the 27 federal units of Brazil, ranking seventh in the number of inhabitants. We examined the allele frequencies of 13 short tandem repeat loci (CFS1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, TH01, vWA, and TPOX), the minimum recommended by the Federal Bureau of Investigation and commonly used in forensic genetics laboratories in Brazil, in a sample of 609 unrelated individuals from all geographic regions of Pernambuco. The allele frequencies ranged from 5 to 47.2%. No significant differences for any loci analyzed were observed compared with other publications in other various regions of Brazil. Most of themarkers observed were in Hardy-Weinberg equilibrium. The occurrence of the allele 47.2 (locus FGA) and alleles 35.1 and 39 (locus D21S11), also described in a single study of the Brazilian population, was observed. The other forensic parameters analyzed (matching probability, power of discrimination, polymorphic information content, paternity exclusion, complement factor I, observed heterozygosity, expected heterozygosity) indicated that the studied markers are very informative for human forensic identification purposes in the Pernambuco population.

Original languageEnglish
Pages (from-to)4303-4310
Number of pages8
JournalGenetics and Molecular Research
Volume14
Issue number2
DOIs
Publication statusPublished - Apr 30 2015

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Keywords

  • Autosomal STRs
  • Human identification
  • Population data

ASJC Scopus subject areas

  • Genetics
  • Molecular Biology

Cite this

Santos, S. M., Souza, C. A., Rabelo, K. C. N., Souza, P., Moura, R. R., Oliveira, T. C., & Crovella, S. (2015). Distribution of forensic marker allelic frequencies in pernambuco, Northestern Brazil. Genetics and Molecular Research, 14(2), 4303-4310. https://doi.org/10.4238/2015.April.30.2