Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro

Sabrina Cattaruzza, Monica Schiappacassi, Åsa Ljungberg-Rose, Paola Spessotto, Daniela Perissinotto, Matthias Mörgelin, Maria Teresa Mucignat, Alfonso Colombatti, Roberto Perris

Research output: Contribution to journalArticlepeer-review

Abstract

We have carried out a comprehensive molecular mapping of PG-M/versican isoforms V0-V3 in adult human tissues and have specifically investigated how the expression of these isoforms is regulated in endothelial cells in vitro. A survey of 21 representative tissues high-lighted a prevalence of V1 mRNA; demonstrated that the relative frequency of expression was V1 > V2 > V3 ≥ V2; and showed that

Original languageEnglish
Pages (from-to)47626-47635
Number of pages10
JournalJournal of Biological Chemistry
Volume277
Issue number49
DOIs
Publication statusPublished - Dec 6 2002

ASJC Scopus subject areas

  • Biochemistry

Fingerprint

Dive into the research topics of 'Distribution of PG-M/versican variants in human tissues and de novo expression of isoform V3 upon endothelial cell activation, migration, and neoangiogenesis in vitro'. Together they form a unique fingerprint.

Cite this