Disturbi della memoria di lavoro verbale in soggetti affetti da morbo di Parkinson

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The present study has been aimed to investigate verbal working memory in patients affected by Parkinson's disease (PD). For this purpose, in two distinct experiments, verbal span tests and the Brown-Peterson procedure have been administered to PD patients and age-matched normal controls. In the verbal span tests, PD patients evidenciated normal sensitivity to word length and frequency effects. A reduced effect of phonological similarity between items in the sequence demonstrated by PD patients in the Experiment 1 was not confirmed in Experiment 2. In the Brown-Peterson procedure, PD patients recalled normally triads of letters when the delay interval was filled by no interferent task or when the interferent task consisted in counting forward or in adding up two one-digit numbers. However, when the retention interval was filled by a serial subtraction task, PD patients recalled significantly less letters than normals. According to the working memory model proposed by Baddeley 2,3 these results document in PD patients normal functioning of the articulatory loop but reduced availability of processing resources in the central executive.

Original languageItalian
JournalNuova Rivista di Neurologia
Issue number3
Publication statusPublished - 1997

ASJC Scopus subject areas

  • Clinical Neurology

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