Diurnal variations in electroconvulsive shock-induced seizures: Involement of endogenous opioids

A. Oliverio, C. Castellano, S. Puglisi-Allegra, P. Renzi

Research output: Contribution to journalArticle

Abstract

Electroconvulsive shock (ECS)-induced seizures present a clear cut diurnal rhythmicity when BALB/c mice are subjected to a light-dark (L/D) schedule. On the contrary, in the absence of external synchronizers no evident fluctuations in epileptic behaviour were evident. Naloxone decreased the threshold of ECS-induced convulsions, thus confirming an involvement of opioids in this type of behaviour. These findings indicate that opioids present a diurnal (L/D) but not circadian (L/L) rhythmicity in BALB/c mice.

Original languageEnglish
Pages (from-to)237-240
Number of pages4
JournalNeuroscience Letters
Volume57
Issue number3
DOIs
Publication statusPublished - Jun 24 1985

Keywords

  • BALB/c mouse
  • circadian rhythm
  • electroconvulsive shock induced seizure
  • opioid

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Diurnal variations in electroconvulsive shock-induced seizures: Involement of endogenous opioids'. Together they form a unique fingerprint.

  • Cite this