Abstract
This study was conducted to evaluate the association between pneumococcal DNA load and parapneumonic pleural effusion (PPE) in children with community-acquired pneumonia. Bacterial load was quantified and related to the presence of PPE with or without empyema in 72 otherwise healthy children aged ≤5 years who were hospitalised because of radiographically confirmed CAP and showed a real-time polymerase chain reaction that was positive for Streptococcus pneumoniae. The proportion of children with a high bacterial load (i.e. ≥265 DNA copies/mL) was larger among the subjects with PPE than those without it. Multivariate analysis showed that a high bacterial load was significantly associated with PPE (OR 8.65; 95 % CI 1.10-67.8 vs a bacterial load of
Original language | English |
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Pages (from-to) | 877-881 |
Number of pages | 5 |
Journal | European Journal of Clinical Microbiology and Infectious Diseases |
Volume | 32 |
Issue number | 7 |
DOIs | |
Publication status | Published - Jul 2013 |
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases