DNA-content variation in mouse spermatozoa arising from irregular meiotic segregation

Carlo Alberto Redi, Ernesto Capanna

Research output: Contribution to journalArticlepeer-review

Abstract

We have examined the DNA coment of spermatozoa from house mouse hybrids between ST.10 chromosome karyotype and Apennine populations with 22 chromosomes, as well as from hybrids between CD and CB strains both possessing 22 chromosomes, but characterized by dissimilar Robertsonian fusions. In the spermatozoa from 22 × ST 40 strains the variations in DNA content were found to fit the variability in gamete ploidy as estimated in spermatids by scoring second meiotic metaphase chromosomes. This demonstrates that during spermiohistogenesis aneuploid spermatids are not eliminated. The rare spermatozoa produced by CD × CB hybrids display a wide variability in their DNA content, with a low percentage of values referable to haploid cells.

Original languageEnglish
Pages (from-to)315-332
Number of pages18
JournalBolletino di zoologia
Volume45
Issue number4
DOIs
Publication statusPublished - Jan 1 1978

ASJC Scopus subject areas

  • Animal Science and Zoology

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