Abstract
DNA damage was evaluated in kidney and liver of mice treated with benzidine at the dose of 150 mg/Kg. The data presented show that the liver can be considered as the target tissue more influenced by the benzidine metabolites. The maxima of DNA fragmentation in the liver and kidney were at 4 and 2 hours respectively after treatment. Moreover the induced DNA damage in kidney and liver of mice treated was evaluated in the time depending from the rate of repair synthesis.
| Translated title of the contribution | DNA damage and repair induced in vivo by benzidine treatment |
|---|---|
| Original language | Italian |
| Pages (from-to) | 1673-1679 |
| Number of pages | 7 |
| Journal | Bollettino della Societa Italiana di Biologia Sperimentale |
| Volume | 56 |
| Issue number | 16 |
| Publication status | Published - Aug 30 1980 |
ASJC Scopus subject areas
- Medicine(all)
Fingerprint Dive into the research topics of 'DNA damage and repair induced in vivo by benzidine treatment'. Together they form a unique fingerprint.
Cite this
Bolognesi, C., Cesarone, C. F., & Santi, L. (1980). Valutazione del danno e del riparo del DNA indotti dal trattamento in vivo con benzidina. Bollettino della Societa Italiana di Biologia Sperimentale, 56(16), 1673-1679.