Abstract
The present work was undertaken to study in hairdressers exposed to several irritants and allergens (prevalently hair-dyeing) and affected by hand contact dermatitis the possible correlation between exposure and direct-oxidative DNA damage, production of tumour necrosis factor alpha (TNFα) and allergic inflammatory disease. We evaluated in 19 hairdressers with hand contact dermatitis, 14 allergic contact dermatitis (ACD) and 5 irritant contact dermatitis (ICD) and in a selected control group TNFα serum levels by ELISA and direct-oxidative DNA damage by Fpg (formamido-pyrimidine-glycosylase) modified Comet test on blood. Hairdressers were divided on the basis of number of hair-dyeing carried out weekly into 2 groups: low-exposure (
| Original language | English |
|---|---|
| Pages (from-to) | 125-129 |
| Number of pages | 5 |
| Journal | Contact Dermatitis |
| Volume | 53 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Sep 2005 |
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Keywords
- Direct-oxidative DNA damage
- Hairdressers
- Hand dermatitis
- TNFα
ASJC Scopus subject areas
- Dermatology
- Toxicology
- Immunology
Cite this
DNA damage and TNFα cytokine production in hairdressers with contact dermatitis. / Cavallo, Delia; Ursini, Cinzia Lucia; Setini, Andrea; Chianese, Concetta; Cristaudo, Antonio; Iavicoli, Sergio.
In: Contact Dermatitis, Vol. 53, No. 3, 09.2005, p. 125-129.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - DNA damage and TNFα cytokine production in hairdressers with contact dermatitis
AU - Cavallo, Delia
AU - Ursini, Cinzia Lucia
AU - Setini, Andrea
AU - Chianese, Concetta
AU - Cristaudo, Antonio
AU - Iavicoli, Sergio
PY - 2005/9
Y1 - 2005/9
N2 - The present work was undertaken to study in hairdressers exposed to several irritants and allergens (prevalently hair-dyeing) and affected by hand contact dermatitis the possible correlation between exposure and direct-oxidative DNA damage, production of tumour necrosis factor alpha (TNFα) and allergic inflammatory disease. We evaluated in 19 hairdressers with hand contact dermatitis, 14 allergic contact dermatitis (ACD) and 5 irritant contact dermatitis (ICD) and in a selected control group TNFα serum levels by ELISA and direct-oxidative DNA damage by Fpg (formamido-pyrimidine-glycosylase) modified Comet test on blood. Hairdressers were divided on the basis of number of hair-dyeing carried out weekly into 2 groups: low-exposure (
AB - The present work was undertaken to study in hairdressers exposed to several irritants and allergens (prevalently hair-dyeing) and affected by hand contact dermatitis the possible correlation between exposure and direct-oxidative DNA damage, production of tumour necrosis factor alpha (TNFα) and allergic inflammatory disease. We evaluated in 19 hairdressers with hand contact dermatitis, 14 allergic contact dermatitis (ACD) and 5 irritant contact dermatitis (ICD) and in a selected control group TNFα serum levels by ELISA and direct-oxidative DNA damage by Fpg (formamido-pyrimidine-glycosylase) modified Comet test on blood. Hairdressers were divided on the basis of number of hair-dyeing carried out weekly into 2 groups: low-exposure (
KW - Direct-oxidative DNA damage
KW - Hairdressers
KW - Hand dermatitis
KW - TNFα
UR - http://www.scopus.com/inward/record.url?scp=24744449300&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=24744449300&partnerID=8YFLogxK
U2 - 10.1111/j.0105-1873.2005.00672.x
DO - 10.1111/j.0105-1873.2005.00672.x
M3 - Article
VL - 53
SP - 125
EP - 129
JO - Contact Dermatitis
JF - Contact Dermatitis
SN - 0105-1873
IS - 3
ER -