DNA damage and TNFα cytokine production in hairdressers with contact dermatitis

Delia Cavallo; Cinzia Lucia Ursini; Andrea Setini; Concetta Chianese; Antonio Cristaudo; Sergio Iavicoli

doi:10.1111/j.0105-1873.2005.00672.x

DNA damage and TNFα cytokine production in hairdressers with contact dermatitis

Delia Cavallo, Cinzia Lucia Ursini, Andrea Setini, Concetta Chianese, Antonio Cristaudo, Sergio Iavicoli

Istituto S. Maria e S. Gallicano

Research output: Contribution to journal › Article

Abstract

The present work was undertaken to study in hairdressers exposed to several irritants and allergens (prevalently hair-dyeing) and affected by hand contact dermatitis the possible correlation between exposure and direct-oxidative DNA damage, production of tumour necrosis factor alpha (TNFα) and allergic inflammatory disease. We evaluated in 19 hairdressers with hand contact dermatitis, 14 allergic contact dermatitis (ACD) and 5 irritant contact dermatitis (ICD) and in a selected control group TNFα serum levels by ELISA and direct-oxidative DNA damage by Fpg (formamido-pyrimidine-glycosylase) modified Comet test on blood. Hairdressers were divided on the basis of number of hair-dyeing carried out weekly into 2 groups: low-exposure (

Original language	English
Pages (from-to)	125-129
Number of pages	5
Journal	Contact Dermatitis
Volume	53
Issue number	3
DOIs	https://doi.org/10.1111/j.0105-1873.2005.00672.x
Publication status	Published - Sep 2005

Keywords

Direct-oxidative DNA damage
Hairdressers
Hand dermatitis
TNFα

ASJC Scopus subject areas

Dermatology
Toxicology
Immunology

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Cavallo, D., Ursini, C. L., Setini, A., Chianese, C., Cristaudo, A., & Iavicoli, S. (2005). DNA damage and TNFα cytokine production in hairdressers with contact dermatitis. Contact Dermatitis, 53(3), 125-129. https://doi.org/10.1111/j.0105-1873.2005.00672.x

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AU - Iavicoli, Sergio

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