Abstract
We report the results of a biological and molecular study carried out on 11 Italian families, with a total of 111 individuals in which adult dominant polycystic kidney disease segregates. A restriction fragment length polymorphism analysis was performed. Two families have shown a genetic heterogeneity even if not phenotypically different from the other ones: they resulted unlinked to 16p markers. A prenatal diagnosis has been performed in a family of the linked type.
| Original language | English |
|---|---|
| Pages (from-to) | 57-59 |
| Number of pages | 3 |
| Journal | European Urology |
| Volume | 21 |
| Issue number | SUPPL. 1 |
| Publication status | Published - 1992 |
Keywords
- Autosomal-dominant polycystic kidney disease
- DNA
- Genetic heterogeneity
- Presymptomatic diagnosis
ASJC Scopus subject areas
- Urology
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Cite this
Venezianoa, L., D'Angelo, A. R., Burrai, L., Perugia, G., Gentile, V., Potenza, L., Iampieri, M. P., Novelletto, A., Novelli, G., & Frontali, M. (1992). DNA markers in diagnosis of adult dominant polycystic kidney disease. European Urology, 21(SUPPL. 1), 57-59.