DNA repair after UV and gamma irradiation. I. Rat spleen cells.

P. Rocchi; P. Perocco; S. Grilli; G. Arfellini; C. Franceschi; A. M. Ferreri; G. Prodi

DNA repair after UV and gamma irradiation. I. Rat spleen cells.

P. Rocchi, P. Perocco, S. Grilli, G. Arfellini, C. Franceschi, A. M. Ferreri, G. Prodi

Istituto Scienze Neurologiche

Research output: Contribution to journal › Article › peer-review

Abstract

An in vitro microculture was set up to standardize DNA enzymatic repair in rat spleen lymphocytes after exposure to ultraviolet or gamma rays by measuring the tritiated thymidine uptake. A relation between irradiation dose and DNA repair is always observable when cell viability and scheduled DNA synthesis are taken into account. This micromethod utilizing rat spleen cells appears to be a suitable system for such a study since it permits a satisfactory evaluation of DNA repair.

Original language	English
Pages (from-to)	67-77
Number of pages	11
Journal	Archivio di scienze biologiche
Volume	60
Issue number	1-4
Publication status	Published - Jan 1976

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "DNA repair after UV and gamma irradiation. I. Rat spleen cells.",

abstract = "An in vitro microculture was set up to standardize DNA enzymatic repair in rat spleen lymphocytes after exposure to ultraviolet or gamma rays by measuring the tritiated thymidine uptake. A relation between irradiation dose and DNA repair is always observable when cell viability and scheduled DNA synthesis are taken into account. This micromethod utilizing rat spleen cells appears to be a suitable system for such a study since it permits a satisfactory evaluation of DNA repair.",

author = "P. Rocchi and P. Perocco and S. Grilli and G. Arfellini and C. Franceschi and Ferreri, {A. M.} and G. Prodi",

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AU - Rocchi, P.

AU - Perocco, P.

AU - Grilli, S.

AU - Arfellini, G.

AU - Franceschi, C.

AU - Ferreri, A. M.

AU - Prodi, G.

PY - 1976/1

Y1 - 1976/1

N2 - An in vitro microculture was set up to standardize DNA enzymatic repair in rat spleen lymphocytes after exposure to ultraviolet or gamma rays by measuring the tritiated thymidine uptake. A relation between irradiation dose and DNA repair is always observable when cell viability and scheduled DNA synthesis are taken into account. This micromethod utilizing rat spleen cells appears to be a suitable system for such a study since it permits a satisfactory evaluation of DNA repair.

AB - An in vitro microculture was set up to standardize DNA enzymatic repair in rat spleen lymphocytes after exposure to ultraviolet or gamma rays by measuring the tritiated thymidine uptake. A relation between irradiation dose and DNA repair is always observable when cell viability and scheduled DNA synthesis are taken into account. This micromethod utilizing rat spleen cells appears to be a suitable system for such a study since it permits a satisfactory evaluation of DNA repair.

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DNA repair after UV and gamma irradiation. I. Rat spleen cells.

Abstract

ASJC Scopus subject areas

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