Abstract
Contrast medium was given intravenously to three non-alcoholic patients who underwent MRI or CT in the acute stage of Wernicke's encephalopathy. Lesions enhancement was not seen in one patient examined within 4 days of clinical onset, was mild in a another 3 days after clinical deterioration and marked in a patient examined 12 days after admission. Contrast enhancement of lesions was present in half of 12 cases of acute disease reported previously. There was a substantial overlap in the time interval between clinical onset and contrast-enhanced CT or MRI in the groups of enhancing and nonenhancing lesions. Since contrast enhancement may be absent in acute WE, proton-density and T2-weighted images are more useful for diagnosis of this reversible but potentially fatal condition.
| Original language | English |
|---|---|
| Pages (from-to) | 249-254 |
| Number of pages | 6 |
| Journal | Neuroradiology |
| Volume | 41 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 1999 |
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Keywords
- Contrast enhancement imaging
- Magnetic resonance
- Wernicke's encephalopathy
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Clinical Neurology
- Radiological and Ultrasound Technology
Cite this
Do acute lesions of Wernicke's encephalopathy show contrast enhancement? Report of three cases and review of the literature. / Mascalchi, M.; Simonelli, P.; Tessa, C.; Giangaspero, F.; Petruzzi, P.; Bosincu, L.; Conti, M.; Sechi, G.; Salvi, F.
In: Neuroradiology, Vol. 41, No. 4, 04.1999, p. 249-254.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Do acute lesions of Wernicke's encephalopathy show contrast enhancement? Report of three cases and review of the literature
AU - Mascalchi, M.
AU - Simonelli, P.
AU - Tessa, C.
AU - Giangaspero, F.
AU - Petruzzi, P.
AU - Bosincu, L.
AU - Conti, M.
AU - Sechi, G.
AU - Salvi, F.
PY - 1999/4
Y1 - 1999/4
N2 - Contrast medium was given intravenously to three non-alcoholic patients who underwent MRI or CT in the acute stage of Wernicke's encephalopathy. Lesions enhancement was not seen in one patient examined within 4 days of clinical onset, was mild in a another 3 days after clinical deterioration and marked in a patient examined 12 days after admission. Contrast enhancement of lesions was present in half of 12 cases of acute disease reported previously. There was a substantial overlap in the time interval between clinical onset and contrast-enhanced CT or MRI in the groups of enhancing and nonenhancing lesions. Since contrast enhancement may be absent in acute WE, proton-density and T2-weighted images are more useful for diagnosis of this reversible but potentially fatal condition.
AB - Contrast medium was given intravenously to three non-alcoholic patients who underwent MRI or CT in the acute stage of Wernicke's encephalopathy. Lesions enhancement was not seen in one patient examined within 4 days of clinical onset, was mild in a another 3 days after clinical deterioration and marked in a patient examined 12 days after admission. Contrast enhancement of lesions was present in half of 12 cases of acute disease reported previously. There was a substantial overlap in the time interval between clinical onset and contrast-enhanced CT or MRI in the groups of enhancing and nonenhancing lesions. Since contrast enhancement may be absent in acute WE, proton-density and T2-weighted images are more useful for diagnosis of this reversible but potentially fatal condition.
KW - Contrast enhancement imaging
KW - Magnetic resonance
KW - Wernicke's encephalopathy
UR - http://www.scopus.com/inward/record.url?scp=0032914278&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032914278&partnerID=8YFLogxK
U2 - 10.1007/s002340050741
DO - 10.1007/s002340050741
M3 - Article
C2 - 10344508
AN - SCOPUS:0032914278
VL - 41
SP - 249
EP - 254
JO - Neuroradiology
JF - Neuroradiology
SN - 0028-3940
IS - 4
ER -