Do acute lesions of Wernicke's encephalopathy show contrast enhancement? Report of three cases and review of the literature

M. Mascalchi, P. Simonelli, C. Tessa, F. Giangaspero, P. Petruzzi, L. Bosincu, M. Conti, G. Sechi, F. Salvi

Research output: Contribution to journalArticlepeer-review

Abstract

Contrast medium was given intravenously to three non-alcoholic patients who underwent MRI or CT in the acute stage of Wernicke's encephalopathy. Lesions enhancement was not seen in one patient examined within 4 days of clinical onset, was mild in a another 3 days after clinical deterioration and marked in a patient examined 12 days after admission. Contrast enhancement of lesions was present in half of 12 cases of acute disease reported previously. There was a substantial overlap in the time interval between clinical onset and contrast-enhanced CT or MRI in the groups of enhancing and nonenhancing lesions. Since contrast enhancement may be absent in acute WE, proton-density and T2-weighted images are more useful for diagnosis of this reversible but potentially fatal condition.

Original languageEnglish
Pages (from-to)249-254
Number of pages6
JournalNeuroradiology
Volume41
Issue number4
DOIs
Publication statusPublished - Apr 1999

Keywords

  • Contrast enhancement imaging
  • Magnetic resonance
  • Wernicke's encephalopathy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Radiological and Ultrasound Technology

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