Do We Need Heparin Coating for Extracorporeal Membrane Oxygenation? New Concepts and Controversial Positions About Coating Surfaces of Extracorporeal Circuits

Simona Silvetti, Andreas Koster, Federico Pappalardo

Research output: Contribution to journalArticle

Abstract

Blood contact with surfaces of the extracorporeal circuit provokes the activation of the coagulation system. To improve biocompatibility of the extracorporeal circuit without increasing the risk of bleeding, coatings of artificial surfaces were designed; many of them involve the use of heparin. Data in the literature show that heparin-induced thrombocytopenia is a major issue in the extracorporeal membrane oxygenation scenario, and no relevant benefits have been shown comparing heparin and no-heparin coating.

Original languageEnglish
Pages (from-to)176-179
Number of pages4
JournalArtificial Organs
Volume39
Issue number2
DOIs
Publication statusPublished - Feb 1 2015

Keywords

  • Blood coagulation-Extracorporeal membrane
  • Oxygenation-Heparin-Circuit coating

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Bioengineering
  • Medicine (miscellaneous)
  • Medicine(all)

Fingerprint Dive into the research topics of 'Do We Need Heparin Coating for Extracorporeal Membrane Oxygenation? New Concepts and Controversial Positions About Coating Surfaces of Extracorporeal Circuits'. Together they form a unique fingerprint.

  • Cite this