Does an apple a day keep the oncologist away?

S. Gallus, R. Talamini, A. Giacosa, M. Montella, V. Ramazzotti, S. Franceschi, E. Negri, C. La Vecchia

Research output: Contribution to journalArticle


Background: Apples have commonly been described as a healthy food. To understand better their role on risk of cancer at several sites, we analyzed data from multicenter case-control studies conducted between 1991 and 2002 in Italy. Patients and methods: The studies included 598 patients with incident cancers of the oral cavity and pharynx, 304 of the oesophagus, 460 of the larynx, 1953 of the colorectum, 2569 of the breast, 1031 of the ovary and 1294 of the prostate. The comparison group included a total of 6629 patients admitted to the same network of hospitals as cases for acute, non-neoplastic diseases. Multivariate odds ratios (OR) were obtained with allowance for age, sex, study center, education, body mass index, tobacco smoking, alcohol drinking, total energy intake, vegetable consumption and physical activity. Results: Compared with subjects reporting consumption of

Original languageEnglish
Pages (from-to)1841-1844
Number of pages4
JournalAnnals of Oncology
Issue number11
Publication statusPublished - Nov 2005


  • Cancer
  • Case-control study
  • Diet
  • Fruit
  • Risk factor

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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  • Cite this

    Gallus, S., Talamini, R., Giacosa, A., Montella, M., Ramazzotti, V., Franceschi, S., Negri, E., & La Vecchia, C. (2005). Does an apple a day keep the oncologist away? Annals of Oncology, 16(11), 1841-1844.