Does immediate breast reconstruction after mastectomy and neoadjuvant chemotherapy influence the outcome of patients with non-endocrine responsive breast cancer?

Research output: Contribution to journalArticle

Abstract

Background/Aim: In breast cancer (BC) patients, breast surgery followed by immediate breast reconstruction (IBR) might favour recurrences and metastases due to extensive surgical manipulation. We retrospectively investigated whether IBR after mastectomy and neoadjuvant chemotherapy (NT) influenced the outcome in patients with early and locally advanced oestrogen receptor (ER)-negative BC. Patients and Methods: Between 1995 and 2006, 133 BC patients received NT followed by total mastectomy, 59 of whom underwent IBR. Patients receiving IBR (IBR group) were compared to patients who did not receive IBR (no-IBR group) over a prolonged median follow-up time (8.2 years). Results: Patients receiving IBR were on average younger than patients not receiving IBR (p

Original languageEnglish
Pages (from-to)6677-6683
Number of pages7
JournalAnticancer Research
Volume34
Issue number11
Publication statusPublished - Nov 1 2014

Keywords

  • Immediate breast reconstruction
  • Invasive breast cancer
  • Locoregional recurrence
  • Non-endocrine responsive patients

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

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