Does immediate breast reconstruction after mastectomy and neoadjuvant chemotherapy influence the outcome of patients with non-endocrine responsive breast cancer?

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6 Citations (Scopus)

Abstract

Background/Aim: In breast cancer (BC) patients, breast surgery followed by immediate breast reconstruction (IBR) might favour recurrences and metastases due to extensive surgical manipulation. We retrospectively investigated whether IBR after mastectomy and neoadjuvant chemotherapy (NT) influenced the outcome in patients with early and locally advanced oestrogen receptor (ER)-negative BC. Patients and Methods: Between 1995 and 2006, 133 BC patients received NT followed by total mastectomy, 59 of whom underwent IBR. Patients receiving IBR (IBR group) were compared to patients who did not receive IBR (no-IBR group) over a prolonged median follow-up time (8.2 years). Results: Patients receiving IBR were on average younger than patients not receiving IBR (p

Original languageEnglish
Pages (from-to)6677-6683
Number of pages7
JournalAnticancer Research
Volume34
Issue number11
Publication statusPublished - Nov 1 2014

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Mammaplasty
Mastectomy
Breast Neoplasms
Drug Therapy
Simple Mastectomy
Estrogen Receptors
Neoplasm Metastasis
Recurrence

Keywords

  • Immediate breast reconstruction
  • Invasive breast cancer
  • Locoregional recurrence
  • Non-endocrine responsive patients

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

Cite this

@article{e03d91a3df654e629a0c2f894459ce27,
title = "Does immediate breast reconstruction after mastectomy and neoadjuvant chemotherapy influence the outcome of patients with non-endocrine responsive breast cancer?",
abstract = "Background/Aim: In breast cancer (BC) patients, breast surgery followed by immediate breast reconstruction (IBR) might favour recurrences and metastases due to extensive surgical manipulation. We retrospectively investigated whether IBR after mastectomy and neoadjuvant chemotherapy (NT) influenced the outcome in patients with early and locally advanced oestrogen receptor (ER)-negative BC. Patients and Methods: Between 1995 and 2006, 133 BC patients received NT followed by total mastectomy, 59 of whom underwent IBR. Patients receiving IBR (IBR group) were compared to patients who did not receive IBR (no-IBR group) over a prolonged median follow-up time (8.2 years). Results: Patients receiving IBR were on average younger than patients not receiving IBR (p",
keywords = "Immediate breast reconstruction, Invasive breast cancer, Locoregional recurrence, Non-endocrine responsive patients",
author = "Gaetano Aurilio and Vincenzo Bagnardi and Rossella Graffeo and Franco Nol{\`e} and Petit, {Jean Yves} and Marzia Locatelli and Stefano Martella and Marco Iera and Piercarlo Rey and Giuseppe Curigliano and Nicole Rotmensz and Elisabetta Munzone and Aron Goldhirsch",
year = "2014",
month = "11",
day = "1",
language = "English",
volume = "34",
pages = "6677--6683",
journal = "Anticancer Research",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "11",

}

TY - JOUR

T1 - Does immediate breast reconstruction after mastectomy and neoadjuvant chemotherapy influence the outcome of patients with non-endocrine responsive breast cancer?

AU - Aurilio, Gaetano

AU - Bagnardi, Vincenzo

AU - Graffeo, Rossella

AU - Nolè, Franco

AU - Petit, Jean Yves

AU - Locatelli, Marzia

AU - Martella, Stefano

AU - Iera, Marco

AU - Rey, Piercarlo

AU - Curigliano, Giuseppe

AU - Rotmensz, Nicole

AU - Munzone, Elisabetta

AU - Goldhirsch, Aron

PY - 2014/11/1

Y1 - 2014/11/1

N2 - Background/Aim: In breast cancer (BC) patients, breast surgery followed by immediate breast reconstruction (IBR) might favour recurrences and metastases due to extensive surgical manipulation. We retrospectively investigated whether IBR after mastectomy and neoadjuvant chemotherapy (NT) influenced the outcome in patients with early and locally advanced oestrogen receptor (ER)-negative BC. Patients and Methods: Between 1995 and 2006, 133 BC patients received NT followed by total mastectomy, 59 of whom underwent IBR. Patients receiving IBR (IBR group) were compared to patients who did not receive IBR (no-IBR group) over a prolonged median follow-up time (8.2 years). Results: Patients receiving IBR were on average younger than patients not receiving IBR (p

AB - Background/Aim: In breast cancer (BC) patients, breast surgery followed by immediate breast reconstruction (IBR) might favour recurrences and metastases due to extensive surgical manipulation. We retrospectively investigated whether IBR after mastectomy and neoadjuvant chemotherapy (NT) influenced the outcome in patients with early and locally advanced oestrogen receptor (ER)-negative BC. Patients and Methods: Between 1995 and 2006, 133 BC patients received NT followed by total mastectomy, 59 of whom underwent IBR. Patients receiving IBR (IBR group) were compared to patients who did not receive IBR (no-IBR group) over a prolonged median follow-up time (8.2 years). Results: Patients receiving IBR were on average younger than patients not receiving IBR (p

KW - Immediate breast reconstruction

KW - Invasive breast cancer

KW - Locoregional recurrence

KW - Non-endocrine responsive patients

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M3 - Article

VL - 34

SP - 6677

EP - 6683

JO - Anticancer Research

JF - Anticancer Research

SN - 0250-7005

IS - 11

ER -