Does malnutrition affect survival in cirrhosis?

Manuela Merli; Oliviero Riggio; Leonard Dally; Livio Capocaccia; Raffaella Lionetti; Massimo De Luca; Maria Anna Guardascione; Massimo Surrenti; Fabio Marra; Palo Gentilini; Gerardo Nardone; Gabriele Budillon; Carmela Loguercio; Camillo Del Vecchio Blanco; Mario Coltorti; Wilfredo Guglielmi; Antonio Francavilla; Giovanni Sandri; Mario Mazzetti Di Pietralata; Rossella Lolli; Giulio Marchesini; Angela Fava; Aido Spadaro; Pietro Paese; Angelo Belmonte; Maria Giovanna Graziani; Marino Luminari; Lorena Accorsi; Sergio Boccia; Franco Colella; Gabriella Tamaro; Gabriele Toigo; Giovanni Pedretti; Franco Fiaccadori; Riccardo Capocaccia

doi:10.1053/jhep.1996.v23.pm0008621131

Does malnutrition affect survival in cirrhosis?

Manuela Merli, Oliviero Riggio, Leonard Dally, Livio Capocaccia, Raffaella Lionetti, Massimo De Luca, Maria Anna Guardascione, Massimo Surrenti, Fabio Marra, Palo Gentilini, Gerardo Nardone, Gabriele Budillon, Carmela Loguercio, Camillo Del Vecchio Blanco, Mario Coltorti, Wilfredo Guglielmi, Antonio Francavilla, Giovanni Sandri, Mario Mazzetti Di Pietralata, Rossella LolliGiulio Marchesini, Angela Fava, Aido Spadaro, Pietro Paese, Angelo Belmonte, Maria Giovanna Graziani, Marino Luminari, Lorena Accorsi, Sergio Boccia, Franco Colella, Gabriella Tamaro, Gabriele Toigo, Giovanni Pedretti, Franco Fiaccadori, Riccardo Capocaccia

Research output: Contribution to journal › Article › peer-review

Abstract

A total of 1,053 cirrhotic patients were included in a prospective study to determine whether malnutrition is a risk factor for mortality in cirrhotic patients. ChildPugh classification as well as clinical and biochemical variables were used to assess the severity of cirrhosis. Nutritional status was evaluated both by anthropometric and clinical measurements. Patients were defined as malnourished when midarm muscle area (MAMA) and/or midarm fat area (MAFA) were below the 5th percentile of an age- and sex-matched population. During follow-up, 419 patients died. The estimated survival rate was 82.7% at 1 year, 65.1% at 3 years, and 50.7% at 5 years. The presence of muscle depletion and/or of a steep reduction in fat deposits was associated with a higher risk of mortality (midarm muscle area,

Original language	English
Pages (from-to)	1041-1046
Number of pages	6
Journal	Hepatology
Volume	23
Issue number	5
DOIs	https://doi.org/10.1053/jhep.1996.v23.pm0008621131
Publication status	Published - 1996

ASJC Scopus subject areas

Hepatology

Access to Document

10.1053/jhep.1996.v23.pm0008621131

Cite this

Merli, M., Riggio, O., Dally, L., Capocaccia, L., Lionetti, R., De Luca, M., Guardascione, M. A., Surrenti, M., Marra, F., Gentilini, P., Nardone, G., Budillon, G., Loguercio, C., Del Vecchio Blanco, C., Coltorti, M., Guglielmi, W., Francavilla, A., Sandri, G., Di Pietralata, M. M., ... Capocaccia, R. (1996). Does malnutrition affect survival in cirrhosis? Hepatology, 23(5), 1041-1046. https://doi.org/10.1053/jhep.1996.v23.pm0008621131

Does malnutrition affect survival in cirrhosis? / Merli, Manuela; Riggio, Oliviero; Dally, Leonard; Capocaccia, Livio; Lionetti, Raffaella; De Luca, Massimo; Guardascione, Maria Anna; Surrenti, Massimo; Marra, Fabio; Gentilini, Palo; Nardone, Gerardo; Budillon, Gabriele; Loguercio, Carmela; Del Vecchio Blanco, Camillo; Coltorti, Mario; Guglielmi, Wilfredo; Francavilla, Antonio; Sandri, Giovanni; Di Pietralata, Mario Mazzetti; Lolli, Rossella; Marchesini, Giulio; Fava, Angela; Spadaro, Aido; Paese, Pietro; Belmonte, Angelo; Graziani, Maria Giovanna; Luminari, Marino; Accorsi, Lorena; Boccia, Sergio; Colella, Franco; Tamaro, Gabriella; Toigo, Gabriele; Pedretti, Giovanni; Fiaccadori, Franco; Capocaccia, Riccardo.

In: Hepatology, Vol. 23, No. 5, 1996, p. 1041-1046.

Research output: Contribution to journal › Article › peer-review

Merli, M, Riggio, O, Dally, L, Capocaccia, L, Lionetti, R, De Luca, M, Guardascione, MA, Surrenti, M, Marra, F, Gentilini, P, Nardone, G, Budillon, G, Loguercio, C, Del Vecchio Blanco, C, Coltorti, M, Guglielmi, W, Francavilla, A, Sandri, G, Di Pietralata, MM, Lolli, R, Marchesini, G, Fava, A, Spadaro, A, Paese, P, Belmonte, A, Graziani, MG, Luminari, M, Accorsi, L, Boccia, S, Colella, F, Tamaro, G, Toigo, G, Pedretti, G, Fiaccadori, F & Capocaccia, R 1996, 'Does malnutrition affect survival in cirrhosis?', Hepatology, vol. 23, no. 5, pp. 1041-1046. https://doi.org/10.1053/jhep.1996.v23.pm0008621131

Merli, Manuela ; Riggio, Oliviero ; Dally, Leonard ; Capocaccia, Livio ; Lionetti, Raffaella ; De Luca, Massimo ; Guardascione, Maria Anna ; Surrenti, Massimo ; Marra, Fabio ; Gentilini, Palo ; Nardone, Gerardo ; Budillon, Gabriele ; Loguercio, Carmela ; Del Vecchio Blanco, Camillo ; Coltorti, Mario ; Guglielmi, Wilfredo ; Francavilla, Antonio ; Sandri, Giovanni ; Di Pietralata, Mario Mazzetti ; Lolli, Rossella ; Marchesini, Giulio ; Fava, Angela ; Spadaro, Aido ; Paese, Pietro ; Belmonte, Angelo ; Graziani, Maria Giovanna ; Luminari, Marino ; Accorsi, Lorena ; Boccia, Sergio ; Colella, Franco ; Tamaro, Gabriella ; Toigo, Gabriele ; Pedretti, Giovanni ; Fiaccadori, Franco ; Capocaccia, Riccardo. / Does malnutrition affect survival in cirrhosis?. In: Hepatology. 1996 ; Vol. 23, No. 5. pp. 1041-1046.

@article{d8547a4a0c6f49a28c338dc62ed94151,

title = "Does malnutrition affect survival in cirrhosis?",

abstract = "A total of 1,053 cirrhotic patients were included in a prospective study to determine whether malnutrition is a risk factor for mortality in cirrhotic patients. ChildPugh classification as well as clinical and biochemical variables were used to assess the severity of cirrhosis. Nutritional status was evaluated both by anthropometric and clinical measurements. Patients were defined as malnourished when midarm muscle area (MAMA) and/or midarm fat area (MAFA) were below the 5th percentile of an age- and sex-matched population. During follow-up, 419 patients died. The estimated survival rate was 82.7% at 1 year, 65.1% at 3 years, and 50.7% at 5 years. The presence of muscle depletion and/or of a steep reduction in fat deposits was associated with a higher risk of mortality (midarm muscle area, ",

author = "Manuela Merli and Oliviero Riggio and Leonard Dally and Livio Capocaccia and Raffaella Lionetti and {De Luca}, Massimo and Guardascione, {Maria Anna} and Massimo Surrenti and Fabio Marra and Palo Gentilini and Gerardo Nardone and Gabriele Budillon and Carmela Loguercio and {Del Vecchio Blanco}, Camillo and Mario Coltorti and Wilfredo Guglielmi and Antonio Francavilla and Giovanni Sandri and {Di Pietralata}, {Mario Mazzetti} and Rossella Lolli and Giulio Marchesini and Angela Fava and Aido Spadaro and Pietro Paese and Angelo Belmonte and Graziani, {Maria Giovanna} and Marino Luminari and Lorena Accorsi and Sergio Boccia and Franco Colella and Gabriella Tamaro and Gabriele Toigo and Giovanni Pedretti and Franco Fiaccadori and Riccardo Capocaccia",

year = "1996",

doi = "10.1053/jhep.1996.v23.pm0008621131",

language = "English",

volume = "23",

pages = "1041--1046",

journal = "Hepatology",

issn = "0270-9139",