Può l'eziologia dell'insufficienza cardiaca modulare la risposta del tono e della reattività autonomica alla riabilitazione cardiovascolare?

Translated title of the contribution: Does the aetiology of heart failure influence the response of autonomic tone and reactivity to cardiovascular rehabilitation?

Gabriella Malfatto, Giovanna Branzi, Beatrice Riva, Luca Sala, Mario Facchini

Research output: Contribution to journalArticlepeer-review

Abstract

We examined if the aetiology of heart failure could influence the favourable autonomic response to cardiovascular rehabilitation. We used the autoregressive spectral analysis of RR intervals variability, obtained from 10 minutes of ECG recording: within each autospectrum, we calculated the power of the low (LH) and high frequency (HF) oscillations: their ratio LF/HF is a useful, well accepted index of the sympathovagal balance. In 43 patients with heart failure we evaluated the autonomic tone at rest, during regular breathing (= stimulation of cardiopulmonary receptors, i.e. a parasympathetic challenge) and during active standing (= sympathetic stimulation). The shift in such autonomic response to 3 months of cardiovascular rehabilitation was analyzed separately for patients with ischemic (n=19) and non-ischemic (n=24) cardiomyopathy. Before rehabilitation, patients with ischemic cardiomyopathy had a higher sympathetic activity at rest, and a preserved response to parasympathetic stimulation. After rehabilitation, both groups of patients showed an improvement in exercise tolerance and performance, no deterioration in ventricular pump function, and a change in the autonomic profile. Thus, the aetiology of heart failure, despite a different baseline sympathovagal balance, does not influence the favourable clinical and autonomic modulation induced by rehabilitation. Independently from the underlying disease, all clinically stable patients with heart failure can benefit from rehabilitation.

Translated title of the contributionDoes the aetiology of heart failure influence the response of autonomic tone and reactivity to cardiovascular rehabilitation?
Original languageItalian
Pages (from-to)101-106
Number of pages6
JournalMonaldi Archives for Chest Disease - Cardiac Series
Volume60
Issue number2
Publication statusPublished - Jun 2003

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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