Abstract
Aim: To compare prognosis of advanced epithelial ovarian cancer (AEOC) patients based on where the first surgical assessment was performed. Patients and Methods: Retrospective analysis of primary AEOC patients was performed and three groups were formed based on where the decision of primary treatment was taken: Internal, if the decision was carried out at our Institution (PDS (Primary Debulking Surgery), I-IDS (Internal-Interval Debulking Surgery)) and Referred in case women were referred after neoadjuvant chemotherapy (NACT) from other Centers (R-IDS (Referred- Interval Debulking Surgery)). Results: Among 573 AEOC, 279 (48.7%) were PDS and 294 (51.3%) IDS. In particular, 134 of 294 (45.6%) were R-IDS and 160 (54.4%) were I-IDS. Median progression-free survival (PFS) was 26 months in PDS, 14 months in I-IDS and 17 months in R-IDS. The difference was statistically significant (p
Original language | English |
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Pages (from-to) | 3027-3032 |
Number of pages | 6 |
Journal | Anticancer Research |
Volume | 35 |
Issue number | 5 |
Publication status | Published - May 1 2015 |
Keywords
- Cytoreduction
- Interval debulking surgery
- Ovarian cancer
- Prognosis
ASJC Scopus subject areas
- Cancer Research
- Oncology
- Medicine(all)