Does tumor growth follow a "universal law"?

Caterina Guiot, Piero Giorgio Degiorgis, Pier Paolo Delsanto, Pietro Gabriele, Thomas S. Deisboeck

Research output: Contribution to journalArticlepeer-review

Abstract

A general model for the ontogenetic growth of living organisms has been recently proposed. Here we investigate the extension of this model to the growth of solid malignant tumors. A variety of in vitro and in vivo data are analysed and compared with the prediction of a "universal" law, relating properly rescaled tumor masses and tumor growth times. The results support the notion that tumor growth follows such a universal law. Several important implications of this finding are discussed, including its relevance for tumor metastasis and recurrence, cell turnover rates, angiogenesis and invasion.

Original languageEnglish
Pages (from-to)147-151
Number of pages5
JournalJournal of Theoretical Biology
Volume225
Issue number2
DOIs
Publication statusPublished - Nov 21 2003

Keywords

  • Angiogenesis
  • Invasion
  • Metastasis
  • Methametical modelling
  • Tumor growth kinetics
  • Tumor therapy
  • Universal law

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Fingerprint Dive into the research topics of 'Does tumor growth follow a "universal law"?'. Together they form a unique fingerprint.

Cite this