Donor hematopoietic cells: Central versus peripheral tolerance

Federica Casiraghi, Norberto Perico, Marina Noris

Research output: Contribution to journalArticlepeer-review

Abstract

The induction and maintenance of tolerance is a multistep, multifaceted process that encompasses clonal deletion of donor-reactive T cells as well as immunoregulatory processes. The implementation of our knowledge into the molecular pathways underlying the activation of these processes and how they are maintained with time would provide new insights to design feasible and safe clinical protocols.

Original languageEnglish
Pages (from-to)284-288
Number of pages5
JournalCurrent Opinion in Organ Transplantation
Volume9
Issue number3
Publication statusPublished - 2004

Keywords

  • Chimerism
  • Clinical transplantation
  • Deletion
  • Hematopoietic cells
  • Regulation

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation

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