Dopamine (DA) regulates many facets of behavior related to reward. Therefore, in order to account for reward-related activities, this neurotransmitter exerts different actions on central neurons. Here we have focused our attention on the electrophysiological effects of DA on neurons that are located in brain areas (frontal cortex, ventral and dorsal striatum, ventral tegmental area) preferentially involved in the determination of sensations linked to incentive, satisfaction, craving, and dependence. It becomes clear that this catecholamine has diverse actions that very likely depend on the functional state and anatomical connections of a given neuron, the type of DA receptors involved, and the activated intracellular messengers.
- Dopaminergic receptors
- Frontal cortex
- Ventral/dorsal ventral mesencephalon
ASJC Scopus subject areas