Dopamine: Cellular Actions

G. Bernardi, N. B. Mercuri

Research output: Chapter in Book/Report/Conference proceedingChapter


Dopamine (DA) regulates many facets of behavior related to reward. Therefore, in order to account for reward-related activities, this neurotransmitter exerts different actions on central neurons. Here we have focused our attention on the electrophysiological effects of DA on neurons that are located in brain areas (frontal cortex, ventral and dorsal striatum, ventral tegmental area) preferentially involved in the determination of sensations linked to incentive, satisfaction, craving, and dependence. It becomes clear that this catecholamine has diverse actions that very likely depend on the functional state and anatomical connections of a given neuron, the type of DA receptors involved, and the activated intracellular messengers.

Original languageEnglish
Title of host publicationEncyclopedia of Neuroscience
PublisherElsevier Ltd
Number of pages4
ISBN (Print)9780080450469
Publication statusPublished - 2010


  • Amphetamine
  • Cocaine
  • Dopamine
  • Dopaminergic receptors
  • Electrophysiology
  • Frontal cortex
  • Striatum
  • Ventral/dorsal ventral mesencephalon

ASJC Scopus subject areas

  • Neuroscience(all)


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