Abstract
The basal release of Met-enkephalin immunoreactive material (ME-IR) from rat striatal slices is doubled by the in vitro addition of 5 × 10-5 M dopamine. The K+ evoked release of ME-IR is alsoslightly enhanced by exposing the slices to dopamine. The effect of dopamine is shared by apomorphine but not by norepinephrine. Neuroleptics do not alter the basal or the K+-stimulated ME-IR release but reverse the dopamine-induced increase. These results suggest that the stimulation of dopamine receptors may influence the enkephalin release within striatum.
Original language | English |
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Pages (from-to) | 364-367 |
Number of pages | 4 |
Journal | Brain Research |
Volume | 293 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb 20 1984 |
Keywords
- dopamine
- Met-enkephalin
- striatum
ASJC Scopus subject areas
- Developmental Biology
- Molecular Biology
- Clinical Neurology
- Neuroscience(all)