Dopamine release in striatal slices of rats previously submitted to electroconvulsive shock

Francesca Passarelli, Enrico Carmenini, Laura Calò, Francesco E. Pontieri

Research output: Contribution to journalArticle

Abstract

The effects of single and repeated electroconvulsive shock (ECS) on the release of dopamine from rat striatal slices were investigated using the fractional release technique. Experiments were performed 24 h after the single or the last of seven ECS sessions. Repeated, but not single, ECS was associated with reduced dopamine release in response to chemical stimulation. These results suggest that repeated ECS affects the regulation of striatal dopamine presynaptic receptors.

Original languageEnglish
Pages (from-to)239-241
Number of pages3
JournalBrain Research
Volume774
Issue number1-2
DOIs
Publication statusPublished - Nov 7 1997

Keywords

  • Dopamine
  • Electroconvulsive shock
  • Fractional release
  • Presynaptic mechanism
  • Striatum

ASJC Scopus subject areas

  • Neuroscience(all)

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