Dopamine transporter immunoreactivity in peripheral blood lymphocytes in Parkinson's disease

B. Caronti, G. Antonini, C. Calderaro, S. Ruggieri, G. Palladini, F. E. Pontieri, C. Colosimo

Research output: Contribution to journalArticle

Abstract

There is increasing interest in the identification of biological markers for the early diagnosis of Parkinson's disease (PD). Previous studies indicate changes of dopamine content, tyrosine hydroxylase immunoreactivity and dopamine receptors in peripheral blood lymphocytes (PBL) in PD. Here we demonstrate a reduction of dopamine transporter immunoreactivity in PBL in the early clinical stages of the disease. These findings contribute to our understanding of the peripheral dopamine system in PD.

Original languageEnglish
Pages (from-to)803-807
Number of pages5
JournalJournal of Neural Transmission
Volume108
Issue number7
DOIs
Publication statusPublished - 2001

Keywords

  • Dopamine
  • Lymphocytes
  • Parkinson's disease

ASJC Scopus subject areas

  • Neuroscience(all)

Fingerprint Dive into the research topics of 'Dopamine transporter immunoreactivity in peripheral blood lymphocytes in Parkinson's disease'. Together they form a unique fingerprint.

  • Cite this